Publications 2023

444.

Jaimes Campos MA, Mavrogeorgis E, Latosinska A, Eder S, Buchwinkler L, Mischak H, Siwy J, Rossing P, Mayer G, Jankowski J.

Urinary peptide analysis to predict the response to blood pressure medication.

Nephrol Dial Transplant. 2023 Oct 31:gfad223. doi: 10.1093/ndt/gfad223. Online ahead of print.

PMID: 37930730

View Abstract:  Free PMC article. Request Reprint

 

443.

Jaimes Campos MA, Andújar I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Mullen W, Schanstra JP, Vlahou A, Rossing K, Peter K, Ortiz A, Campbell A, Persson F, Latosinska A, Mischak H, Siwy J, Jankowski J.

Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study.

Pharmaceuticals (Basel). 2023 Sep 14;16(9):1298. doi: 10.3390/ph16091298.

PMID: 37765106

View Abstract:  Free PMC article. Request Reprint

 

442.

Hobson S, Mavrogeorgis E, He T, Siwy J, Ebert T, Kublickiene K, Stenvinkel P, Mischak H.

Urine Peptidome Analysis Identifies Common and Stage-Specific Markers in Early Versus Advanced CKD.

Proteomes. 2023 Aug 23;11(3):25. doi: 10.3390/proteomes11030025.

PMID: 37755704

View Abstract:  Free PMC article. Request Reprint

 

441.

Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A, Jankowski V.

Multiple urinary peptides display distinct sex-specific distribution.

Proteomics. 2023 Sep 26:e2300227. doi: 10.1002/pmic.202300227. Online ahead of print.

PMID: 37750242

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440.

Keller F, Beige J, Siwy J, Mebazaa A, An D, Mischak H, Schanstra JP, Mokou M, Perco P, Staessen JA, Vlahou A, Latosinska A.

Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios.

J Transl Med. 2023 Sep 24;21(1):663. doi: 10.1186/s12967-023-04508-6.

PMID: 37741989

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439.

Mavrogeorgis E, He T, Mischak H, Latosinska A, Vlahou A, Schanstra JP, Catanese L, Amann K, Huber TB, Beige J, Rupprecht H, Siwy J.

Urinary peptidomic liquid biopsy for non-invasive differential diagnosis of chronic kidney disease.

Nephrol Dial Transplant. 2023 Sep 11:gfad200. doi: 10.1093/ndt/gfad200. Online ahead of print.

PMID: 37697716

View Abstract:  Free PMC article. Request Reprint

 

438.

Lohia S, Siwy J, Mavrogeorgis E, Eder S, Thöni S, Mayer G, Mischak H, Vlahou A, Jankowski V.

Exploratory Study Analyzing the Urinary Peptidome of T2DM Patients Suggests Changes in ECM but Also Inflammatory and Metabolic Pathways Following GLP-1R Agonist Treatment.

Int J Mol Sci. 2023 Aug 31;24(17):13540. doi: 10.3390/ijms241713540.

PMID: 37686344

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437.

de Beer D, Mels CM, Schutte AE, Delles C, Mary S, Mullen W, Mischak H, Kruger R.

Urinary Peptidomics and Pulse Wave Velocity: The African-PREDICT Study.

J Proteome Res. 2023 Oct 6;22(10):3282-3289. doi: 10.1021/acs.jproteome.3c00347. Epub 2023 Sep 9.

PMID: 37688558

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436.

Boutin L, Latosinska A, Mischak H, Deniau B, Asakage A, Legrand M, Gayat E, Mebazaa A, Chadjichristos CE, Depret F.

Subclinical and clinical acute kidney injury share similar urinary peptide signatures and prognosis.

Intensive Care Med. 2023 Oct;49(10):1191-1202. doi: 10.1007/s00134-023-07198-2. Epub 2023 Sep 5.

PMID: 37670154

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435.

Mischak H.

Further comments on 'A classifier based on 273 urinary peptides predicts early renal damage in primary hypertension'.

J Hypertens. 2023 Oct 1;41(10):1667. doi: 10.1097/HJH.0000000000003524.

PMID: 37642595

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434.

Mischak H.

Comment on 'A classifier based on 273 urinary peptides predicts early renal damage in primary hypertension' by Lin et al.

J Hypertens. 2023 Oct 1;41(10):1666. doi: 10.1097/HJH.0000000000003489.

PMID: 37642594

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433.

Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A, Jankowski V.

Multiple urinary peptides display distinct sex-specific distribution.

Proteomics. 2023 Sep 26:e2300227. doi: 10.1002/pmic.202300227.

PMID: 37750242

View Abstract:  Free PMC article. Request Reprint

 

432.

Keller F, Beige J, Siwy J, Mebazaa A, An D, Mischak H, Schanstra JP, Mokou M, Perco P, Staessen JA, Vlahou A, Latosinska A.

Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios.

J Transl Med. 2023 Sep 24;21(1):663. doi: 10.1186/s12967-023-04508-6.

PMID: 37741989

View Abstract:  Free PMC article. Request Reprint

 

431.

Jaimes Campos MA, Andújar I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Mullen W, Schanstra JP, Vlahou A, Rossing K, Peter K, Ortiz A, Campbell A, Persson F, Latosinska A, Mischak H, Siwy J, Jankowski J.

Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study.

Pharmaceuticals (Basel). 2023 Sep 14;16(9):1298. doi: 10.3390/ph16091298.

PMID: 37765106

View Abstract:  Free PMC article. Request Reprint

 

430.

Mavrogeorgis E, He T, Mischak H, Latosinska A, Vlahou A, Schanstra JP, Catanese L, Amann K, Huber TB, Beige J, Rupprecht H, Siwy J.

Urinary peptidomic liquid biopsy for non-invasive differential diagnosis of chronic kidney disease.

Nephrol Dial Transplant. 2023 Sep 11:gfad200. doi: 10.1093/ndt/gfad200.

PMID: 37697716

View Abstract:  Free PMC article. Request Reprint

 

429.

Lohia S, Siwy J, Mavrogeorgis E, Eder S, Thöni S, Mayer G, Mischak H, Vlahou A, Jankowski V.

Exploratory Study Analyzing the Urinary Peptidome of T2DM Patients Suggests Changes in ECM but Also Inflammatory and Metabolic Pathways Following GLP-1R Agonist Treatment.

Int J Mol Sci. 2023 Aug 31;24(17):13540. doi: 10.3390/ijms241713540.

PMID: 37686344

View Abstract:  Free PMC article. Request Reprint

 

428.

Hobson S, Mavrogeorgis E, He T, Siwy J, Ebert T, Kublickiene K, Stenvinkel P, Mischak H.

Urine Peptidome Analysis Identifies Common and Stage-Specific Markers in Early Versus Advanced CKD.

Proteomes. 2023 Aug 23;11(3):25. doi: 10.3390/proteomes11030025.

PMID: 37755704

View Abstract:  Free PMC article. Request Reprint

427.

Latosinska A, Frantzi M, Siwy J.

Peptides as "better biomarkers"? Value, challenges, and potential solutions to facilitate implementation​.

Mass Spectrom Rev. 2023 Jun 26. doi: 10.1002/mas.21854. Online ahead of print.

PMID: 37357849

View Abstract:  Free PMC article. Request Reprint

 

426.

Marx D, Anglicheau D, Caillard S, Moulin B, Kochman A, Mischak H, Latosinska A, Bienaimé F, Prié D, Marquet P, Perrin P, Gwinner W, Metzger J.

Urinary collagen peptides: Source of markers for bone metabolic processes in kidney transplant recipients.

Proteomics Clin Appl. 2023 Jun 27:e2200118. doi: 10.1002/prca.202200118. Online ahead of print.

PMID: 37365945

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425.

Peters B, Beige J, Siwy J, Rudnicki M, Wendt R, Ortiz A, Sanz AB, Mischak H, Reich HN, Nasic S, Mahmood D, Persson A, Fernström A, Weiner M, Stegmayr B; PersTIgAN working group.

Dynamics of urine proteomics biomarker and disease progression in patients with IgA nephropathy.

Nephrol Dial Transplant. 2023 Jun 22:gfad125. doi: 10.1093/ndt/gfad125. Online ahead of print.

PMID: 37349951

View Abstract:  Free PMC article. Request Reprint

 

424.

Chori BS, An DW, Martens DS, Yu YL, Gilis-Malinowska N, Abubakar SM, Ibrahim EA, Ajanya O, Abiodun OO, Anya T, Tobechukwu I, Isiguzo G, Cheng HM, Chen CH, Liao CT, Mokwatsi G, Stolarz-Skrzypek K, Wojciechowska W, Narkiewicz K, Rajzer M, Brguljan-Hitij J, Nawrot TS, Asayama K, Reyskens P, Mischak H, Odili AN, Staessen JA; UPRIGHT-HTM Investigators.

Urinary proteomics combined with home blood pressure telemonitoring for health care reform trial-First progress report.

J Clin Hypertens (Greenwich). 2023 Jun;25(6):521-533. doi: 10.1111/jch.14664. Epub 2023 May 6.

PMID: 37147930

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423.

De Beer D, Mels CMC, Schutte AE, Delles C, Mary S, Mullen W, Latosinska A, Mischak H, Kruger R.

Identifying a urinary peptidomics profile for hypertension in young adults: The African-PREDICT study: Urinary peptidomics and hypertension: Urinary peptidomics and hypertension.

Proteomics. 2023 Jun;23(11):e2200444. doi: 10.1002/pmic.202200444. Epub 2023 Apr 3.

PMID: 36943111

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422.

Devos H, Zoidakis J, Roubelakis MG, Latosinska A, Vlahou A.

Reviewing the Regulators of COL1A1.

Int J Mol Sci. 2023 Jun 11;24(12):10004. doi: 10.3390/ijms241210004.

PMID: 37373151

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421.

Catanese L, Siwy J, Mischak H, Wendt R, Beige J, Rupprecht H.

Recent Advances in Urinary Peptide and Proteomic Biomarkers in Chronic Kidney Disease: A Systematic Review.

Int J Mol Sci. 2023 May 23;24(11):9156. doi: 10.3390/ijms24119156.

PMID: 37298105

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420.

Davison BA, Edwards C, Cotter G, Kimmoun A, Gayat É, Latosinska A, Mischak H, Takagi K, Deniau B, Picod A, Mebazaa A.

Plasma and Urinary Biomarkers Improve Prediction of Mortality through 1 Year in Intensive Care Patients: An Analysis from FROG-ICU.

J Clin Med. 2023 May 6;12(9):3311. doi: 10.3390/jcm12093311.

PMID: 37176751

View Abstract:  Free PMC article. Request Reprint

 

419.

An DW, Yu YL, Martens DS, Latosinska A, Zhang ZY, Mischak H, Nawrot TS, Staessen JA.

Statistical approaches applicable in managing OMICS data: Urinary proteomics as exemplary case.

Mass Spectrom Rev. 2023 May 4. doi: 10.1002/mas.21849. Online ahead of print.

PMID: 37143314 

View Abstract:  Free PMC article. Request Reprint

 

418.

Degenaar A, Jacobs A, Kruger R, Delles C, Mischak H, Mels C.

Cardiovascular risk and kidney function profiling using conventional and novel biomarkers in young adults: the African-PREDICT study.

BMC Nephrol. 2023 Apr 13;24(1):96. doi: 10.1186/s12882-023-03100-w.

PMID: 37055746 

View Abstract:  Free PMC article. Request Reprint

 

417.

Rotbain Curovic V, Tofte N, Lindhardt M, Adamova K, Bakker SJL, Beige J, Beulens JWJ, Birkenfeld AL, Currie G, Delles C, Dimos I, Francová L, Frimodt-Møller M, Girman P, Göke R, Hansen TW, Havrdova T, Kooy A, Laverman GD, Mischak H, Navis G, Nijpels G, Noutsou M, Ortiz A, Parvanova A, Persson F, Petrie JR, Ruggenenti PL, Rutters F, Rychlík I, Siwy J, Spasovski G, Speeckaert M, Trillini M, Zürbig P, von der Leyen H, Rossing P; on the behalf of the PRIORITY Study Group.

Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria - A post-hoc analysis of the PRIORITY randomized clinical trial.

J Diabetes Complications. 2023 Apr;37(4):108433. doi: 10.1016/j.jdiacomp.2023.108433. Epub 2023 Feb 18.

PMID: 36841085

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416.

Wei D, Melgarejo JD, Van Aelst L, Vanassche T, Verhamme P, Janssens S, Peter K, Zhang ZY.

Prediction of Coronary Artery Disease Using Urinary Proteomics.

Eur J Prev Cardiol. 2023 Mar 21:zwad087. doi: 10.1093/eurjpc/zwad087. Online ahead of print.

PMID: 36943304

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415.

Lohia S, Latosinska A, Zoidakis J, Makridakis M, Mischak H, Glorieux G, Vlahou A, Jankowski V.

Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD.

Int J Mol Sci. 2023 Mar 11;24(6):5402. doi: 10.3390/ijms24065402.

PMID: 36982475

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414.

Massy ZA, Lambert O, Metzger M, Sedki M, Chaubet A, Breuil B, Jaafar A, Tack I, Nguyen-Khoa T, Alves M, Siwy J, Mischak H, Verbeke F, Glorieux G, Herpe YE, Schanstra JP, Stengel B, Klein J; CKD-REIN study group.

Machine Learning-Based Urine Peptidome Analysis to Predict and Understand Mechanisms of Progression to Kidney Failure.

Kidney Int Rep. 2022 Dec 12;8(3):544-555. doi: 10.1016/j.ekir.2022.11.023. eCollection 2023 Mar.

PMID: 36938091

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413.

Mokou M, Mischak H, Frantzi M.

Statistical determination of cancer biomarkers: moving forward clinically.

Expert Rev Mol Diagn. 2023 Mar;23(3):187-189. doi: 10.1080/14737159.2023.2187290. Epub 2023 Mar 6.

PMID: 36877119

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412.

Frantzi M, Culig Z, Heidegger I, Mokou M, Latosinska A, Roesch MC, Merseburger AS, Makridakis M, Vlahou A, Blanca-Pedregosa A, Carrasco-Valiente J, Mischak H, Gomez-Gomez E.

Mass Spectrometry-Based Biomarkers to Detect Prostate Cancer: A Multicentric Study Based on Non-Invasive Urine Collection without Prior Digital Rectal Examination.

Cancers (Basel). 2023 Feb 11;15(4):1166. doi: 10.3390/cancers15041166.

PMID: 36831508

View Abstract:  Free PMC article. Request Reprint

 

411.

de Beer D, Mels CMC, Schutte AE, Delles C, Mary S, Mullen W, Mischak H, Kruger R.

A urinary peptidomics approach for early stages of cardiovascular disease risk: The African-PREDICT study.

Hypertens Res. 2023 Feb;46(2):485-494. doi: 10.1038/s41440-022-01097-7. Epub 2022 Nov 17.

PMID: 36396816

View Abstract:  Free PMC article. Request Reprint

 

410.

Mokou M, Narayanasamy S, Stroggilos R, Balaur IA, Vlahou A, Mischak H, Frantzi M.

A Drug Repurposing Pipeline Based on Bladder Cancer Integrated Proteotranscriptomics Signatures.

Methods Mol Biol. 2023;2684:59-99. doi: 10.1007/978-1-0716-3291-8_4.

PMID: 37410228

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