Publications 2021

380.

Rudnicki M, Siwy J, Wendt R, Lipphardt M, Koziolek MJ, Maixnerova D, Peters B, Kerschbaum J, Leierer J, Neprasova M, Banasik M, Sanz AB, Perez-Gomez MV, Ortiz A, Stegmayr B, Tesar V, Mischak H, Beige J, Reich HN

Urine proteomics for prediction of disease progression in patients with IgA nephropathy.

PERSTIGAN working group.Nephrol Dial Transplant. 2021 Dec 31;37(1):42-52. doi: 10.1093/ndt/gfaa307.

PMID: 33313853

View Abstract:  Free PMC article. Request Reprint

 

379.

Mavrogeorgis E, Mischak H, Latosinska A, Vlahou A, Schanstra JP, Siwy J, Jankowski V, Beige J, Jankowski J.

Collagen-Derived Peptides in CKD: A Link to Fibrosis.

Toxins (Basel). 2021 Dec 23;14(1):10. doi: 10.3390/toxins14010010.

PMID: 35050988

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378.

Sanchez-Martin I, Magalhães P, Ranjzad P, Fatmi A, Richard F, Manh TPV, Saurin AJ, Feuillet G, Denis C, Woolf AS, Schanstra JP, Zürbig P, Caubit X, Fasano L.

Haploinsufficiency of the mouse Tshz3 gene leads to kidney defects.

Hum Mol Genet. 2021 Dec 17:ddab362. doi: 10.1093/hmg/ddab362. Online ahead of print.

PMID: 34919690

View Abstract:  Free PMC article. Request Reprint

 

377.

Wendt R, Siwy J, He T, Latosinska A, Wiech T, Zipfel PF, Tserga A, Vlahou A, Rupprecht H, Catanese L, Mischak H, Beige J.

Molecular Mapping of Urinary Complement Peptides in Kidney Diseases.

Proteomes. 2021 Dec 13;9(4):49. doi: 10.3390/proteomes9040049.

PMID: 34941814

View Abstract:  Free PMC article. Request Reprint

 

376.

Mavrogeorgis E, Mischak H, Latosinska A, Siwy J, Jankowski V, Jankowski J.

Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS.

Molecules. 2021 Nov 30;26(23):7260. doi: 10.3390/molecules26237260.

PMID: 34885840

View Abstract:  Free PMC article. Request Reprint

 

375.

Martens DS, Thijs L, Latosinska A, Trenson S, Siwy J, Zhang ZY, Wang C, Beige J, Vlahou A, Janssens S, Mischak H, Nawrot TS, Staessen JA.

Urinary peptidomic profiles to address age-related disabilities: a prospective population study.

FLEMENGHO investigators.Lancet Healthy Longev. 2021 Nov;2(11):e690-e703. doi: 10.1016/S2666-7568(21)00226-9.

PMID: 34766101

View Abstract:  Free PMC article. Request Reprint

 

374.

He T, Mischak M, Clark AL, Campbell RT, Delles C, Díez J, Filippatos G, Mebazaa A, McMurray JJV, González A, Raad J, Stroggilos R, Bosselmann HS, Campbell A, Kerr SM, Jackson CE, Cannon JA, Schou M, Girerd N, Rossignol P, McConnachie A, Rossing K, Schanstra JP, Zannad F, Vlahou A, Mullen W, Jankowski V, Mischak H, Zhang Z, Staessen JA, Latosinska A.

Urinary peptides in heart failure: a link to molecular pathophysiology.

Eur J Heart Fail. 2021 Nov;23(11):1875-1887. doi: 10.1002/ejhf.2195. Epub 2021 May 7.

PMID: 33881206

View Abstract:  Free PMC article. Request Reprint

 

373.

Rambabova-Bushljetik I, Metzger J, Siwy J, Dohcev S, Bushljetikj O, Filipce V, Trajceska L, Mischak H, Spasovski G.

Association of the chronic kidney disease urinary proteomic predictor CKD273 with clinical risk factors of graft failure in kidney allograft recipients.

Nephrol Dial Transplant. 2021 Oct 11:gfab297. doi: 10.1093/ndt/gfab297. Online ahead of print.

PMID: 34634117

View Abstract:  Free PMC article. Request Reprint

 

372.

Aiquel LL, Pitta J, Antonoglou GN, Mischak I, Sailer I, Payer M.

Does the timing of implant placement and loading influence biological outcomes of implant-supported multiple-unit fixed dental prosthesis-A systematic review with meta-analyses.

Clin Oral Implants Res. 2021 Oct;32 Suppl 21:5-27. doi: 10.1111/clr.13860.

PMID: 34642990 Review.

View Abstract:  Free PMC article. Request Reprint

 

371.

Latosinska A, Siwy J, Cherney DZ, Perkins BA, Mischak H, Beige J.

SGLT2-Inhibition reverts urinary peptide changes associated with severe COVID-19: An in-silico proof-of-principle of proteomics-based drug repurposing.

Proteomics. 2021 Oct;21(20):e2100160. doi: 10.1002/pmic.202100160. Epub 2021 Sep 15.

PMID: 34477316

View Abstract:  Free PMC article. Request Reprint

 

370.

Thijs L, Asayama K, Maestre GE, Hansen TW, Buyse L, Wei DM, Melgarejo JD, Brguljan-Hitij J, Cheng HM, de Souza F, Gilis-Malinowska N, Kawecka-Jaszcz K, Mels C, Mokwatsi G, Muxfeldt ES, Narkiewicz K, Odili AN, Rajzer M, Schutte AE, Stolarz-Skrzypek K, Tsai YW, Vanassche T, Vanholder R, Zhang ZY, Verhamme P, Kruger R, Mischak H, Staessen JA.

Urinary proteomics combined with home blood pressure telemonitoring for health care reform trial: rational and protocol.

UPRIGHT-HTM Investigators; Coordinating, Logistic; Recruiting, and; Urinary Proteomics Centres,; Advisors.Blood Press. 2021 Oct;30(5):269-281. doi: 10.1080/08037051.2021.1952061. Epub 2021 Aug 30.

PMID: 34461803

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369.

Siwy J, Wendt R, Albalat A, He T, Mischak H, Mullen W, Latosinska A, Lübbert C, Kalbitz S, Mebazaa A, Peters B, Stegmayr B, Spasovski G, Wiech T, Staessen JA, Wolf J, Beige J.

CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology?

Proteomics. 2021 Oct;21(20):e2100133. doi: 10.1002/pmic.202100133. Epub 2021 Aug 21.

PMID: 34383378

View Abstract:  Free PMC article. Request Reprint

 

368.

Rotbain Curovic V, Magalhães P, He T, Hansen TW, Mischak H, Rossing P.

Urinary peptidome and diabetic retinopathy in the DIRECT-Protect 1 and 2 trials.

DIRECT Programme Study Group.Diabet Med. 2021 Sep;38(9):e14634. doi: 10.1111/dme.14634. Epub 2021 Jul 18.

PMID: 34228837 Clinical Trial.

View Abstract:  Free PMC article. Request Reprint

 

367.

Petra E, He T, Lygirou V, Latosinska A, Mischak H, Vlahou A, Jankowski J.

Urine peptidome analysis in cardiorenal syndrome reflects molecular processes.

Sci Rep. 2021 Aug 10;11(1):16219. doi: 10.1038/s41598-021-95695-z.

PMID: 34376786

View Abstract:  Free PMC article. Request Reprint

 

366.

Bannaga A, Metzger J, Voigtländer T, Pejchinovski M, Frantzi M, Book T, James S, Gopalakrishnan K, Mischak H, Manns MP, Arasaradnam RP.

Pathophysiological Implications of Urinary Peptides in Hepatocellular Carcinoma.

.Cancers (Basel). 2021 Jul 27;13(15):3786. doi: 10.3390/cancers13153786.

PMID: 34359689

View Abstract:  Free PMC article. Request Reprint

 

365.

Catanese L, Siwy J, Mavrogeorgis E, Amann K, Mischak H, Beige J, Rupprecht H.

A Novel Urinary Proteomics Classifier for Non-Invasive Evaluation of Interstitial Fibrosis and Tubular Atrophy in Chronic Kidney Disease.

Proteomes. 2021 Jul 13;9(3):32. doi: 10.3390/proteomes9030032.

PMID: 34287333

View Abstract:  Free PMC article. Request Reprint

 

364.

Hupe MC, Hempel MC, Rodler S, Frantzi M, Mischak H, Merseburger AS, Stief CG, Chaloupka M.

[Diagnostic markers in urology].

Urologe A. 2021 Jun 22. doi: 10.1007/s00120-021-01568-8. Online ahead of print.
 
PMID: 34156515
 
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363.

Mokou M, Frantzi M, Mischak H, Vlahou A, Latosinska A.

Developing novel drug candidates and repurposed drugs for prostate cancer based on molecular profiles.

Curr Med Chem. 2021 May 25. doi: 10.2174/0929867328666210525162730. Online ahead of print.
 
PMID: 34036903
 
View Abstract:  Free PMC article. Request Reprint

 

362.

Wendt R, Thijs L, Kalbitz S, Mischak H, Siwy J, Raad J, Metzger J, Neuhaus B, Leyen HV, Dudoignon E, Mebazaa A, Spasovski G, Milenkova M, Canevska-Talevska A, Czerwieńska B, Wiecek A, Peters B, Nilsson Å, Schwab M, Rothfuss K, Lübbert C, Staessen JA, Beige J

A urinary peptidomic profile predicts outcome in SARS-CoV-2-infected patients.

CRIT-COV-U investigators. EClinicalMedicine. 2021 May 3:100883. doi: 10.1016/j.eclinm.2021.100883. Online ahead of print.
 
PMID: 33969282
 
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361.

Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhães P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zürbig P, Doucet A, Umbhauer M, Cereghini S.

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.

Dis Model Mech. 2021 May 1;14(5):dmm047498. doi: 10.1242/dmm.047498. Epub 2021 May 4.
 
PMID: 33737325
 
View Abstract:  Free PMC article. Request Reprint
 
 
360.

Tailliar M, Schanstra JP, Dierckx T, Breuil B, Hanouna G, Charles N, Bascands JL, Dussol B, Vazi A, Chiche L, Siwy J, Faguer S, Daniel L, Daugas E, Jourde-Chiche N,

Urinary Peptides as Potential Non-Invasive Biomarkers for Lupus Nephritis: Results of the Peptidu-LUP Study.

On Behalf Of The Groupe Coopératif Sur le Lupus Rénal Gclr. J Clin Med. 2021 Apr 14;10(8):1690. doi: 10.3390/jcm10081690.
 
PMID: 33920017
 
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359.

Siwy J, Mischak H, Beige J, Rossing P, Stegmayr B.

Biomarkers for early detection of kidney disease: a call for pathophysiological relevance.

Kidney Int. 2021 May;99(5):1240-1241. doi: 10.1016/j.kint.2021.02.008.
 
PMID: 33892861
 
View Abstract:  Free PMC article. Request Reprint

 

358.

He T, Mischak M, Clark AL, Campbell RT, Delles C, Díez J, Filippatos G, Mebazaa A, McMurray JJV, González A, Raad J, Stroggilos R, Bosselmann HS, Campbell A, Kerr SM, Jackson CE, Cannon JA, Schou M, Girerd N, Rossignol P, McConnachie A, Rossing K, Schanstra JP, Zannad F, Vlahou A, Mullen W, Jankowski V, Mischak H, Zhang Z, Staessen JA, Latosinska A.

Urinary peptides in heart failure: a link to molecular pathophysiology.

Eur J Heart Fail. 2021 Apr 21. doi: 10.1002/ejhf.2195. Online ahead of print.
 
PMID: 33881206
 
View Abstract:  Free PMC article. Request Reprint

 

357.

He T, Zhang Z, Staessen JA, Mischak H, Latosinska A, Beige J.

Proteomic Biomarkers in the Cardiorenal Syndrome: Toward Deciphering Molecular Pathophysiology.

Am J Hypertens. 2021 Apr 2:hpaa201. doi: 10.1093/ajh/hpaa201. Online ahead of print.
 
PMID: 33821948
 
View Abstract:  Free PMC article. Request Reprint

 

356.

Mavrogeorgis E, Mischak H, Beige J, Latosinska A, Siwy J.

Understanding glomerular diseases through proteomics.

Expert Rev Proteomics. 2021 Feb;18(2):137-157. doi: 10.1080/14789450.2021.1908893. Epub 2021 Apr 8.
 
PMID: 33779448
 
View Abstract:  Free PMC article. Request Reprint

 

355.

Gomez-Cabrero D, Walter S, Abugessaisa I, Miñambres-Herraiz R, Palomares LB, Butcher L, Erusalimsky JD, Garcia-Garcia FJ, Carnicero J, Hardman TC, Mischak H, Zürbig P, Hackl M, Grillari J, Fiorillo E, Cucca F, Cesari M, Carrie I, Colpo M, Bandinelli S, Feart C, Peres K, Dartigues JF, Helmer C, Viña J, Olaso G, García-Palmero I, Martínez JG, Jansen-Dürr P, Grune T, Weber D, Lippi G, Bonaguri C, Sinclair AJ, Tegner J, Rodriguez-Mañas L

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts.

FRAILOMIC initiative. Geroscience. 2021 Jun;43(3):1317-1329. doi: 10.1007/s11357-021-00334-0. Epub 2021 Feb 18.
 
PMID: 33599920
 
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354.

Vlahou A, Hallinan D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Céraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, Kamat AM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Dräger BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C, Vanholder R.

Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics?

Hypertension. 2021 Apr;77(4):1029-1035. doi: 10.1161/HYPERTENSIONAHA.120.16340. Epub 2021 Feb 15.
 
PMID: 33583200
 
View Abstract:  Free PMC article. Request Reprint

 

353.

Magalhães P, Zürbig P, Mischak H, Schleicher E. Clin Kidney J.

Urinary fetuin-A peptides as a new marker for impaired kidney function in patients with type 2 diabetes.

2020 Oct 23;14(1):269-276. doi: 10.1093/ckj/sfaa176. eCollection 2021 Jan.
 
PMID: 33564428
 
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352.

He T, Melgarejo JD, Clark AL, Yu YL, Thijs L, Díez J, López B, González A, Cleland JG, Schanstra JP, Vlahou A, Latosinska A, Mischak H, Staessen JA, Zhang ZY, Jankowski V.

Serum and urinary biomarkers of collagen type-I turnover predict prognosis in patients with heart failure.

Clin Transl Med. 2021 Jan;11(1):e267. doi: 10.1002/ctm2.267.
 
PMID: 33463057
 
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