Publications 2016

241.
Magalhães P, Mischak H, Zürbig P.
Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases.
Curr Opin Nephrol Hypertens. 2016 Nov;25(6):494-501.

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240.
Frantzi M, Klimou Z, Makridakis M, Zoidakis J, Latosinska A, Borràs DM, Janssen B, Giannopoulou I, Lygirou V, Lazaris AC, Anagnou NP, Mischak H, Roubelakis MG, Vlahou A.
Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models.
Oncotarget. 2016 Sep 23. doi: 10.18632/oncotarget.12218. [Epub ahead of print]

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239.
Ortiz A, Husi H, Gonzalez-Lafuente L, Valiño-Rivas L, Fresno M, Sanz AB, Mullen W, Albalat A, Mezzano S, Vlahou T, Mischak H, Sanchez-Niño MD.
Mitogen-Activated Protein Kinase 14 Promotes AKI.
J Am Soc Nephrol. 2016 Sep 12. pii: ASN.2015080898. [Epub ahead of print]

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238.
Krochmal M, Fernandes M, Filip S, Pontillo C, Husi H, Zoidakis J, Mischak H, Vlahou A, Jankowski J.
PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease.
Database (Oxford). 2016 Sep 1;2016. pii: baw128. doi: 10.1093/database/baw128. Print 2016.

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237.
Klein J, Ramirez-Torres A, Ericsson A, Huang Y, Breuil B, Siwy J, Mischak H, Peng XR, Bascands JL, Schanstra JP.
Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice.
Kidney Int. 2016 Nov;90(5):1045-1055. doi: 10.1016/j.kint.2016.06.023.

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236.
Zhang Z, Ravassa S, Yang WY, Petit T, Petra Z, Lopez B, Wei FF, Pontillo C, Thijs L, Jacobs L, Gonzalez A, Koeck T, Christian D, Voigt JU, Verhamme P, Kuznetsova T, Diez J, Mischak H, Staessen JA.
[OP.7C.07] DIASTOLIC LEFT VENTRICULAR FUNCTION IN RELATION TO COLLAGEN-SPECIFIC URINARY AND SERUM COLLAGEN BIOMARKERS IN A GENERAL POPULATION.
J Hypertens. 2016 Sep;34 Suppl 2:e91-2. doi: 10.1097/01.hjh.0000491572.80267.23.

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235.
Currie G, Flynn J, Lindhardt M, Mischak H, Rossing P, Delles C.
[OP.1D.10] THE CKD273 URINARY PROTEOMIC CLASSIFIER IS NOT A MARKER OF GENERALISED VASCULAR DISEASE IN TYPE 2 DIABETIC PATIENTS WITH NORMAL RENAL FUNCTION.
J Hypertens. 2016 Sep;34 Suppl 2:e14. doi: 10.1097/01.hjh.0000491365.78962.52.

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234.
Lindhardt M, Persson F, Zürbig P, Stalmach A, Mischak H, de Zeeuw D, Lambers Heerspink H, Klein R, Orchard T, Porta M, Fuller J, Bilous R, Chaturvedi N, Parving HH, Rossing P.
Urinary proteomics predict onset of microalbuminuria in normoalbuminuric type 2 diabetic patients, a sub-study of the DIRECT-Protect 2 study.
Nephrol Dial Transplant. 2016 Aug 8. pii: gfw292. [Epub ahead of print]

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233.
Pontillo C, Jacobs L, Staessen JA, Schanstra JP, Rossing P, Heerspink HJ, Siwy J, Mullen W, Vlahou A, Mischak H, Vanholder R, Zürbig P, Jankowski J.
A urinary proteome-based classifier for the early detection of decline in glomerular filtration.
Nephrol Dial Transplant. 2016 Jul 6. pii: gfw239. [Epub ahead of print]

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232.
Pejchinovski M, Siwy J, Metzger J, Dakna M, Mischak H, Klein J, Jankowski V, Bae KT, Chapman AB, Kistler AD.
Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression.
Nephrol Dial Transplant. 2016 Jul 5. pii: gfw243. [Epub ahead of print]

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231.
Bhat A, Mokou M, Zoidakis J, Jankowski V, Vlahou A, Mischak H.
BcCluster: A Bladder Cancer Database at the Molecular Level.
Bladder Cancer. 2016 Jan 7;2(1):65-76.

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230.
Pena MJ, Mischak H, Heerspink HJ.
Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease.
Diabetologia. 2016 Sep;59(9):1819-31. doi: 10.1007/s00125-016-4001-9. Epub 2016 Jun 25. Review.

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229.
Rossing K, Bosselmann HS, Gustafsson F, Zhang ZY, Gu YM, Kuznetsova T, Nkuipou-Kenfack E, Mischak H, Staessen JA, Koeck T, Schou M.
Urinary Proteomics Pilot Study for Biomarker Discovery and Diagnosis in Heart Failure with Reduced Ejection Fraction.
PLoS One. 2016 Jun 16;11(6):e0157167. doi: 10.1371/journal.pone.0157167. eCollection 2016.

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228.
Metzger J, Mullen W, Husi H, Stalmach A, Herget-Rosenthal S, Groesdonk HV, Mischak H, Klingele M.
Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study.
Crit Care. 2016 May 26;20(1):157. doi: 10.1186/s13054-016-1344-z.

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227.
Farmakis D, Koeck T, Mullen W, Parissis J, Gogas BD, Nikolaou M, Lekakis J, Mischak H, Filippatos G.
Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates.
Eur J Heart Fail. 2016 Jul;18(7):822-9. doi: 10.1002/ejhf.544. Epub 2016 May 25.

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226.
Latosinska A, Makridakis M, Frantzi M, Borràs DM, Janssen B, Mullen W, Zoidakis J, Merseburger AS, Jankowski V, Mischak H, Vlahou A.
Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings.
Sci Rep. 2016 May 11;6:25619. doi: 10.1038/srep25619.

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225.
Carrick E, Vanmassenhove J, Glorieux G, Metzger J, Dakna M, Pejchinovski M, Jankowski V, Mansoorian B, Husi H, Mullen W, Mischak H, Vanholder R, Van Biesen W.
Development of a MALDI MS-based platform for early detection of acute kidney injury.
Proteomics Clin Appl. 2016 Apr 27. doi: 10.1002/prca.201500117. [Epub ahead of print]

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224.
Neisius U, Koeck T, Mischak H, Rossi SH, Olson E, Carty DM, Dymott JA, Dominiczak AF, Berry C, Oldroyd KG, Delles C.
Urine proteomics in the diagnosis of stable angina.
BMC Cardiovasc Disord. 2016 Apr 19;16(1):70. doi: 10.1186/s12872-016-0246-y.

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223.
Frantzi M, Van Kessel KE, Zwarthoff EC, Marquez M, Rava M, Malats N, Merseburger AS, Katafigiotis I, Stravodimos K, Mullen W, Zoidakis J, Makridakis M, Pejchinovski M, Critselis E, Lichtinghagen R, Brand K, Dakna M, Roubelakis MG, Theodorescu D, Vlahou A, Mischak H, Anagnou NP.
Development and validation of urine-based peptide biomarker panels for detecting bladder cancer in a multi-center study.
Clin Cancer Res. 2016 Mar 29. pii: clincanres.2715.2015. [Epub ahead of print]

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222.
Lindhardt M, Persson F, Currie G, Pontillo C, Beige J, Delles C, von der Leyen H, Mischak H, Navis G, Noutsou M, Ortiz A, Ruggenenti PL, Rychlik I, Spasovski G, Rossing P.
Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial.
BMJ Open. 2016 Mar 2;6(3):e010310. doi: 10.1136/bmjopen-2015-010310.

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221.
Pontillo C, Mischak H.
Urinary biomarkers to predict CKD: is the future in multi-marker panels?
Nephrol Dial Transplant. 2016 Feb 29. pii: gfv467. [Epub ahead of print] Review. No abstract available.

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220.
Stepczynska A, Schanstra JP, Mischak H.
Implementation of CE-MS-identified proteome-based biomarker panels in drug development and patient management.
Bioanalysis. 2016 Mar;8(5):439-55. doi: 10.4155/bio.16.8. Epub 2016 Feb 19.

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219.
Klein J, Bascands JL, Mischak H, Schanstra JP.
The role of urinary peptidomics in kidney disease research.
Kidney Int. 2016 Mar;89(3):539-45. doi: 10.1016/j.kint.2015.10.010. Epub 2016 Jan 14.

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218.
Schönemeier B, Metzger J, Klein J, Husi H, Bremer B, Armbrecht N, Dakna M, Schanstra JP, Rosendahl J, Wiegand J, Jäger M, Mullen W, Breuil B, Plentz RR, Lichtinghagen R, Brand K, Kühnel F, Mischak H, Manns MP, Lankisch TO.
Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis.
Pancreas. 2016 Jan 18. [Epub ahead of print]

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