Publications 2022


Martens DS, Mischak H, Nawrot TS, Staessen JA; FLEMENGHO investigators.

A urinary proteomic marker indicative of premature ageing.

Blood Press Monit. 2022 Dec 1;27(Suppl 1):e9. doi: 10.1097/01.mbp.0000905240.53184.3c.

PMID: 36445437

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Persu A, Fanelli E, Latosinska A, Mischak H.

The urinary proteomic profile of fibromuscular dysplasia.

Blood Press Monit. 2022 Dec 1;27(Suppl 1):e8-e9. doi: 10.1097/01.mbp.0000905236.23950.d5.

PMID: 36445436

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Mischak H.

Urinary proteomics for risk stratification.

Blood Press Monit. 2022 Dec 1;27(Suppl 1):e7. doi: 10.1097/01.mbp.0000905220.68670.f2.

PMID: 36445432

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de Beer D, Mels CMC, Schutte AE, Delles C, Mary S, Mullen W, Mischak H, Kruger R.

A urinary peptidomics approach for early stages of cardiovascular disease risk: The African-PREDICT study.

Hypertens Res. 2022 Nov 17. doi: 10.1038/s41440-022-01097-7.

PMID: 36396816

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Piedrafita A, Siwy J, Klein J, Akkari A, Amaya-Garrido A, Mebazaa A, Sanz AB, Breuil B, Montero Herrero L, Marcheix B, Depret F, Fernandez L, Tardif E, Minville V, Alves M, Metzger J; Kidney Attack Study Group, Grossac J, Mischak H, Ortiz A, Gazut S, Schanstra JP, Faguer S, Mayeur N, Casemayou A, Labaste F.

A universal predictive and mechanistic urinary peptide signature in acute kidney injury.

Crit Care. 2022 Nov 7;26(1):344. doi: 10.1186/s13054-022-04193-9.

PMID: 36345008

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Mengual L, Frantzi M, Mokou M, Ingelmo-Torres M, Vlaming M, Merseburger AS, Roesch MC, Culig Z, Alcaraz A, Vlahou A, Mischak H, Van der Heijden AG.

Multicentric validation of diagnostic tests based on BC-116 and BC-106 urine peptide biomarkers for bladder cancer in two prospective cohorts of patients.

Br J Cancer. 2022 Nov;127(11):2043-2051. doi: 10.1038/s41416-022-01992-3.

PMID: 36192490

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Rambabova-Bushljetik I, Metzger J, Siwy J, Dohcev S, Bushljetikj O, Filipce V, Trajceska L, Mischak H, Spasovski G.

Association of the chronic kidney disease urinary proteomic predictor CKD273 with clinical risk factors of graft failure in kidney allograft recipients.

Nephrol Dial Transplant. 2022 Sep 22;37(10):2014-2021. doi: 10.1093/ndt/gfab297.

PMID: 34634117

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Curovic RV, Eickhoff MK, Rönkkö T, Frimodt-Møller M, Hansen TW, Mischak H, Rossing P, Ahluwalia TS, Persson F.

Dapagliflozin Improves the Urinary Proteomic Kidney-Risk Classifier CKD273 in Type 2 Diabetes with Albuminuria - a Randomized Clinical Trial.

Diabetes Care. 2022 Aug 23:dc221157. doi: 10.2337/dc22-1157. Online ahead of print.

PMID: 35998283

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Frantzi M, Heidegger I, Roesch MC, Gomez-Gomez E, Steiner E, Vlahou A, Mullen W, Guler I, Merseburger AS, Mischak H, Culig Z.

Validation of diagnostic nomograms based on CE-MS urinary biomarkers to distinguish clinically significant prostate cancer.

World J Urol 2022 Jul 16. doi: 10.1007/s00345-022-04077-1.

PMID: 35581445

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Marx D, Anglicheau D, Caillard S, Moulin B, Kochman A, Mischak H, Pejchinowski M, Latosinska A, Bienaimé F, Prié D, Marquet P, Perrin P, Gwinner W, Metzger J.

Urinary collagen-derived peptides as sensitive markers for bone resorption and bisphosphonate treatment in kidney transplant patients.

medRxiv preprint server 2022.

doi: 2022.02.15.22270979



Staessen JA, Wendt R, Yu YL, Kalbitz S, Thijs L, Siwy J, Raad J, Metzger J, Neuhaus B, Papkalla A, von der Leyen H, Mebazaa A, Dudoignon E, Spasovski G, Milenkova M, Canevska-Taneska A, Psichogiou M, Rajzer MW, Fulawka L, Dzitkowska-Zabielska M, Weiss G, Feldt T, Stegemann M, Normark J, Zoufaly A, Schmiedel S, Seilmaier M, Rumpf B, Banasik M, Krajewska M, Catanese L, Rupprecht H, Czerwienska B, Peters B, Nilsson Å, Rothfuss K, Lübbert C, Mischak H, Beige J, the CRIT-Cov-U investigators

Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a cohort study.

Lancet Digit Health. 2022 Oct;4(10):e727-e737. doi: 10.1097/01.mbp.0000905240.53184.3c.

PMID: 36057526

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Nikolaou PE, Mylonas N, Makridakis M, Makrecka-Kuka M, Iliou A, Zerikiotis S, Efentakis P, Kampoukos S, Kostomitsopoulos N, Vilskersts R, Ikonomidis I, Lambadiari V, Zuurbier CJ, Latosinska A, Vlahou A, Dimitriadis G, Iliodromitis EK, Andreadou I.

Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?

Basic Res Cardiol. 2022 May 17;117(1):27. doi: 10.1007/s00395-022-00934-7.

PMID: 35581445

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Stroggilos R, Frantzi M, Zoidakis J, Mokou M, Moulavasilis N, Mavrogeorgis E, Melidi A, Makridakis M, Stravodimos K, Roubelakis MG, Mischak H, Vlahou A.

Gene Expression Monotonicity across Bladder Cancer Stages Informs on the Molecular Pathogenesis and Identifies a Prognostic Eight-Gene Signature.

Cancers (Basel). 2022 May 21;14(10):2542. doi: 10.3390/cancers14102542.

PMID: 35626146

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Jäger M, Latosinska A, Herten M, Busch A, Grupp T, Sowislok A.

The Implant Proteome-The Right Surgical Glue to Fix Titanium Implants In Situ.

J. Funct Biomater. 2022 Apr 15;13(2):44. doi: 10.3390/jfb13020044.

PMID: 35466226

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O'Connell SP, Frantzi M, Latosinska A, Webb M, Mullen W, Pejchinovski M, Salji M, Mischak H, Cooper CS, Clark J, Brewer DS,

A Model to Detect Significant Prostate Cancer Integrating Urinary Peptide and Extracellular Vesicle RNA Data.

On Behalf Of The Movember Gap Urine Biomarker Consortium.Cancers (Basel). 2022 Apr 14;14(8):1995. doi: 10.3390/cancers14081995.

PMID: 35454901

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Wei D, Trenson S, Van Keer JM, Melgarejo J, Cutsforth E, Thijs L, He T, Latosinska A, Ciarka A, Vanassche T, Van Aelst L, Janssens S, Van Cleemput J, Mischak H, Staessen JA, Verhamme P, Zhang ZY.

The novel proteomic signature for cardiac allograft vasculopathy.

ESC Heart Fail. 2022 Apr;9(2):1216-1227. doi: 10.1002/ehf2.13796. Epub 2022 Jan 10.

PMID: 35005846

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Nicol K, Mansoorian B, Latosinska A, Koutroulaki A, Mullen B, Combet E.

No evidence of differential impact of sunflower and rapeseed oil on biomarkers of coronary artery disease or chronic kidney disease in healthy adults with overweight and obesity: result from a randomised control trial.

Eur J Nutr. 2022 Apr 5. doi: 10.1007/s00394-022-02810-5. Online ahead of print.

PMID: 35381848

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Mischak H, Kalvodova L.

Interview with Harald Mischak.

Proteomics. 2022 Feb;22(3):e2100390. doi: 10.1002/pmic.202100390.

PMID: 35112791 No abstract available.

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Tserga A, Pouloudi D, Saulnier-Blache JS, Stroggilos R, Theochari I, Gakiopoulou H, Mischak H, Zoidakis J, Schanstra JP, Vlahou A, Makridakis M.

Proteomic Analysis of Mouse Kidney Tissue Associates Peroxisomal Dysfunction with Early Diabetic Kidney Disease.

Biomedicines. 2022 Jan 20;10(2):216. doi: 10.3390/biomedicines10020216.

PMID: 35203426

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Latosinska A, Bruno RM, Pappaccogli M, Bacca A, Beauloye C, Boutouyrie P, Khettab H, Staessen JA, Taddei S, Toubiana L, Vikkula M, Mischak H, Persu A.

Increased Collagen Turnover Is a Feature of Fibromuscular Dysplasia and Associated With Hypertrophic Radial Remodeling: A Pilot, Urine Proteomic Study.

Hypertension. 2022 Jan;79(1):93-103. doi: 10.1161/HYPERTENSIONAHA.121.18146. Epub 2021 Nov 17.

PMID: 34788057

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Petra E, Siwy J, Vlahou A, Jankowski J.

Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease.

PLoS One. 2022 Jan 19;17(1):e0262667. doi: 10.1371/journal.pone.0262667. eCollection 2022.

PMID: 35045102

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