Publications 2021
528.
Rudnicki M, Siwy J, Wendt R, Lipphardt M, Koziolek MJ, Maixnerova D, Peters B, Kerschbaum J, Leierer J, Neprasova M, Banasik M, Sanz AB, Perez-Gomez MV, Ortiz A, Stegmayr B, Tesar V, Mischak H, Beige J, Reich HN; PERSTIGAN working group.
Urine proteomics for prediction of disease progression in patients with IgA nephropathy
Nephrol Dial Transplant. 2021, 37(1):42-52.
527.
Mavrogeorgis E, Mischak H, Latosinska A, Vlahou A, Schanstra JP, Siwy J, Jankowski V, Beige J, Jankowski J.
Collagen-Derived Peptides in CKD: A Link to Fibrosis
Toxins (Basel). 2021, 14(1):10.
526.
Wendt R, Siwy J, He T, Latosinska A, Wiech T, Zipfel PF, Tserga A, Vlahou A, Rupprecht H, Catanese L, Mischak H, Beige J.
Molecular Mapping of Urinary Complement Peptides in Kidney Diseases
Proteomes. 2021, 9(4):49.
525.
Rönkkö TKE, Eickhoff MK, Mischak H, Rossing P, Persson F, Ahluwalia TS.
Urinary proteomics and the effect of dapagliflozin treatment in persons with type 2 diabetes and diabetic kidney disease: a randomised crossover trial
Diabetologia 2021, 64(Suppl1):106.
524.
Stroggilos R, Frantzi M, Zoidakis J, Mavrogeorgis E, Mokou M, Melidi A, Roubelakis MG, Mischak H, Vlahou A.
Gene expression and coexpression analysis of the entire bladder cancer clinical stage spectrum
Eur Urol Open Sci 2021, 32(Suppl2):S180.
523.
Wei DM, Zhang Z, Trenson S, Van Keer J, Melgarejo J, Yu Y, Thijs L, Van Aelst L, Vanassche T, Janssens S.
Larger-scale proteomic analysis highlights pathogenetic pathways underlying cardiac allograft vasculopathy and potential novel treatment targets
Acta Cardiologica. 2021, 76:22–23.
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522.
Mavrogeorgis E, Mischak H, Latosinska A, Siwy J, Jankowski V, Jankowski J.
Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS
Molecules. 2021, 26(23):7260.
521.
Martens DS, Thijs L, Latosinska A, Trenson S, Siwy J, Zhang ZY, Wang C, Beige J, Vlahou A, Janssens S, Mischak H, Nawrot TS, Staessen JA; FLEMENGHO investigators.
Urinary peptidomic profiles to address age-related disabilities: a prospective population study
Lancet Healthy Longev. 2021, 2(11):e690-e703.
520.
He T, Mischak M, Clark AL, Campbell RT, Delles C, Díez J, Filippatos G, Mebazaa A, McMurray JJV, González A, Raad J, Stroggilos R, Bosselmann HS, Campbell A, Kerr SM, Jackson CE, Cannon JA, Schou M, Girerd N, Rossignol P, McConnachie A, Rossing K, Schanstra JP, Zannad F, Vlahou A, Mullen W, Jankowski V, Mischak H, Zhang Z, Staessen JA, Latosinska A.
Urinary peptides in heart failure: a link to molecular pathophysiology
Eur J Heart Fail. 2021, 23(11):1875-1887. Epub 2021 May 7.
519.
Latosinska A, Siwy J, Cherney DZ, Perkins BA, Mischak H, Beige J.
SGLT2-Inhibition reverts urinary peptide changes associated with severe COVID-19: An in-silico proof-of-principle of proteomics-based drug repurposing
Proteomics. 2021, 21(20):e2100160. Epub 2021 Sep 15.
518.
Thijs L, Asayama K, Maestre GE, Hansen TW, Buyse L, Wei DM, Melgarejo JD, Brguljan-Hitij J, Cheng HM, de Souza F, Gilis-Malinowska N, Kawecka-Jaszcz K, Mels C, Mokwatsi G, Muxfeldt ES, Narkiewicz K, Odili AN, Rajzer M, Schutte AE, Stolarz-Skrzypek K, Tsai YW, Vanassche T, Vanholder R, Zhang ZY, Verhamme P, Kruger R, Mischak H, Staessen JA; UPRIGHT-HTM Investigators; Coordinating, Logistic; Recruiting, and; Urinary Proteomics Centres; Advisors.
Urinary proteomics combined with home blood pressure telemonitoring for health care reform trial: rational and protocol
Blood Press. 2021, 30(5):269-281. Epub 2021 Aug 30.
517.
Siwy J, Wendt R, Albalat A, He T, Mischak H, Mullen W, Latosinska A, Lübbert C, Kalbitz S, Mebazaa A, Peters B, Stegmayr B, Spasovski G, Wiech T, Staessen JA, Wolf J, Beige J.
CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology?
Proteomics. 2021, 21(20):e2100133. Epub 2021 Aug 21.
516.
Hupe MC, Hempel MC, Rodler S, Frantzi M, Mischak H, Merseburger AS, Stief CG, Chaloupka M.
[Diagnostic markers in urology]
Urologe A. 2021, 60(10):1323-1330.
515.
Rotbain Curovic V, Magalhães P, He T, Hansen TW, Mischak H, Rossing P; DIRECT Programme Study Group.
Urinary peptidome and diabetic retinopathy in the DIRECT-Protect 1 and 2 trials
Diabet Med. 2021, 38(9):e14634. Epub 2021 Jul 18.
514.
Petra E, He T, Lygirou V, Latosinska A, Mischak H, Vlahou A, Jankowski J.
Urine peptidome analysis in cardiorenal syndrome reflects molecular processes
Sci Rep. 2021, 11(1):16219.
513.
He T, Zhang Z, Staessen JA, Mischak H, Latosinska A, Beige J.
Proteomic Biomarkers in the Cardiorenal Syndrome: Toward Deciphering Molecular Pathophysiology
Am J Hypertens. 2021, 34(7):669-679.
512.
Bannaga A, Metzger J, Voigtländer T, Pejchinovski M, Frantzi M, Book T, James S, Gopalakrishnan K, Mischak H, Manns MP, Arasaradnam RP.
Pathophysiological Implications of Urinary Peptides in Hepatocellular Carcinoma
Cancers (Basel). 2021, 13(15):3786.
511.
Catanese L, Siwy J, Mavrogeorgis E, Amann K, Mischak H, Beige J, Rupprecht H.
A Novel Urinary Proteomics Classifier for Non-Invasive Evaluation of Interstitial Fibrosis and Tubular Atrophy in Chronic Kidney Disease
Proteomes. 2021, 9(3):32.
510.
Wendt R, Thijs L, Kalbitz S, Mischak H, Siwy J, Raad J, Metzger J, Neuhaus B, Leyen HV, Dudoignon E, Mebazaa A, Spasovski G, Milenkova M, Canevska-Talevska A, Czerwieńska B, Wiecek A, Peters B, Nilsson Å, Schwab M, Rothfuss K, Lübbert C, Staessen JA, Beige J; CRIT-COV-U investigators.
A urinary peptidomic profile predicts outcome in SARS-CoV-2-infected patients
EClinicalMedicine. 2021, 36:100883. Epub 2021 May 3.
509.
Gomez-Cabrero D, Walter S, Abugessaisa I, Miñambres-Herraiz R, Palomares LB, Butcher L, Erusalimsky JD, Garcia-Garcia FJ, Carnicero J, Hardman TC, Mischak H, Zürbig P, Hackl M, Grillari J, Fiorillo E, Cucca F, Cesari M, Carrie I, Colpo M, Bandinelli S, Feart C, Peres K, Dartigues JF, Helmer C, Viña J, Olaso G, García-Palmero I, Martínez JG, Jansen-Dürr P, Grune T, Weber D, Lippi G, Bonaguri C, Sinclair AJ, Tegner J, Rodriguez-Mañas L; FRAILOMIC initiative.
A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts
Geroscience. 2021, 43(3):1317-1329. Epub 2021 Feb 18.
508.
Siwy J, Mischak H, Beige J, Rossing P, Stegmayr B.
Biomarkers for early detection of kidney disease: a call for pathophysiological relevance
Kidney Int. 2021, 99(5):1240-1241.
507.
Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhães P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zürbig P, Doucet A, Umbhauer M, Cereghini S.
Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model
Dis Model Mech. 2021, 14(5):dmm047498. Epub 2021 May 4.
506.
Verbeke F, Siwy J, Van Biesen W, Mischak H, Pletinck A, Schepers E, Neirynck N, Magalhães P, Pejchinovski M, Pontillo C, Lichtinghagen R, Brand K, Vlahou A, De Bacquer D, Glorieux G.
The urinary proteomics classifier chronic kidney disease 273 predicts cardiovascular outcome in patients with chronic kidney disease
Nephrol Dial Transplant. 2021, 36(5):811-818.
505.
Tailliar M, Schanstra JP, Dierckx T, Breuil B, Hanouna G, Charles N, Bascands JL, Dussol B, Vazi A, Chiche L, Siwy J, Faguer S, Daniel L, Daugas E, Jourde-Chiche N, On Behalf Of The Groupe Coopératif Sur le Lupus Rénal Gclr.
Urinary Peptides as Potential Non-Invasive Biomarkers for Lupus Nephritis: Results of the Peptidu-LUP Study
J Clin Med. 2021, 10(8):1690.
504.
Wei DM, Melgarejo J, Thijs L, Ciarka A, Vanassche T, Van Aelst L, Janssens S, Mischak H, Staessen JA, Verhamme P, Zhang ZY.
The urinary proteomic profile of arterial stiffness in the general population
European Heart Journal
2021, 42(Suppl 1):ehab724.3392.
503.
Hupe MC, Hempel MC, Rodler S, Frantzi M, Mischak H, Merseburger AS, Stief CG, Chaloupka M.
Diagnostische Marker in der Urologie
Der Urologe
2021, 60(10):1323–1330.
502.
Vlahou A, Hallinan D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Céraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, Kamat AM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Dräger BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C, Vanholder R.
Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics?
Hypertension. 2021, 77(4):1029-1035. Epub 2021 Feb 15.
501.
Ahluwalia TS, Rönkkö TK, Eickhoff MK, Mischak H, Rossing P, Persson F.
PO2029 Urinary Proteomics and Effects of Dapagliflozin Treatment in Persons with Type 2 Diabetes and Kidney Disease Journal of the American Society of Nephrology. 2021;32(10S):623.
500.
Klein J, Buffin-Meyer B, Boizard F, Moussaoui N, Lescat O, Breuil B, Fedou C, Feuillet G, Casemayou A, Neau E, Hindryckx A, Decatte L, Levtchenko E, Raaijmakers A, Vayssière C, Goua V, Lucas C, Perrotin F, Cloarec S, Benachi A, Manca-Pellissier MC, Delmas HL, Bessenay L, Le Vaillant C, Allain-Launay E, Gondry J, Boudailliez B, Simon E, Prieur F, Lavocat MP, Saliou AH, De Parscau L, Bidat L, Noel C, Floch C, Bourdat-Michel G, Favre R, Weingertner AS, Oury JF, Baudouin V, Bory JP, Pietrement C, Fiorenza M, Massardier J, Kessler S, Lounis N, Auriol FC, Marcorelles P, Collardeau-Frachon S, Zürbig P, Mischak H, Magalhães P, Batut J, Blader P, Saulnier Blache JS, Bascands JL, Schaefer F, Decramer S, Schanstra JP; BIOMAN consortium.
Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease
Kidney Int. 2021, 99(3):737-749. Epub 2020 Aug 1.
499.
Mavrogeorgis E, Mischak H, Beige J, Latosinska A, Siwy J.
Understanding glomerular diseases through proteomics
Expert Rev Proteomics. 2021, 18(2):137-157. Epub 2021 Apr 8.
498.
Mokou M, Frantzi M, Mischak H, Vlahou A, Latosinska A.
Developing Novel Drug Candidates and Repurposed Drugs for Prostate Cancer Based on Molecular Profiles
Curr Med Chem. 2021, 28(40):8392-8415.
497.
He T, Melgarejo JD, Clark AL, Yu YL, Thijs L, Díez J, López B, González A, Cleland JG, Schanstra JP, Vlahou A, Latosinska A, Mischak H, Staessen JA, Zhang ZY, Jankowski V.
Serum and urinary biomarkers of collagen type-I turnover predict prognosis in patients with heart failure
Clin Transl Med. 2021, 11(1):e267.
496.
Latosinska A, Siwy J, Faguer S, Beige J, Mischak H, Schanstra JP.
Value of Urine Peptides in Assessing Kidney and Cardiovascular Disease
Proteomics Clin Appl. 2021, 15(1):e2000027. Epub 2020 Aug 16.
495.
He T, Pejchinovski M, Mullen W, Beige J, Mischak H, Jankowski V.
Peptides in Plasma, Urine, and Dialysate: Toward Unravelling Renal Peptide Handling
Proteomics Clin Appl. 2021, 15(1):e2000029. Epub 2020 Jul 23.