Publications 2016


351.

Zhang ZY, Ravassa S, Yang WY, Petit T, Pejchinovski M, Zürbig P, López B, Wei FF, Pontillo C, Thijs L, Jacobs L, González A, Koeck T, Delles C, Voigt JU, Verhamme P, Kuznetsova T, Díez J, Mischak H, Staessen JA.

Diastolic Left Ventricular Function in Relation to Urinary and Serum Collagen Biomarkers in a General Population

PLoS One. 2016 Dec 13;11(12):e0167582.


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350.

Stanley E, Delatola EI, Nkuipou-Kenfack E, Spooner W, Kolch W, Schanstra JP, Mischak H, Koeck T.

Comparison of different statistical approaches for urinary peptide biomarker detection in the context of coronary artery disease

BMC Bioinformatics. 2016, 6;17(1):496.


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349.

Magalhães P, Schanstra JP, Carrick E, Mischak H, Zürbig P.

Urinary biomarkers for renal tract malformations

Expert Rev Proteomics. 2016, 13(12):1121-1129.


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348.
Magalhães P, Mischak H, Zürbig P.

Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases
Curr Opin Nephrol Hypertens. 2016, 25(6):494-501.


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347.
Frantzi M, Klimou Z, Makridakis M, Zoidakis J, Latosinska A, Borràs DM, Janssen B, Giannopoulou I, Lygirou V, Lazaris AC, Anagnou NP, Mischak H, Roubelakis MG, Vlahou A.

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models
Oncotarget. 2016, 7(43):70750-70768.


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346.
Krochmal M, Fernandes M, Filip S, Pontillo C, Husi H, Zoidakis J, Mischak H, Vlahou A, Jankowski J.

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease
Database (Oxford). 2016, 2016:baw128.


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345.

Barrera-Ocampo A, Arlt S, Matschke J, Hartmann U, Puig B, Ferrer I, Zürbig P, Glatzel M, Sepulveda-Falla D, Jahn H.

Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

J Neuropathol Exp Neurol. 2016, 75(9):903-16. Epub 2016 Aug 2.


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344.

Martín-Pozuelo G, González-Barrio R, Barberá GG, Albalat A, García-Alonso J, Mullen W, Mischak H, Periago MJ.

Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis

Int J Mol Sci. 2016, 17(11):1789.


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343.
Klein J, Ramirez-Torres A, Ericsson A, Huang Y, Breuil B, Siwy J, Mischak H, Peng XR, Bascands JL, Schanstra JP.

Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice
Kidney Int. 2016, 90(5):1045-1055. Epub 2016 Aug 12.


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342.

Reich M, Dacheva I, Nobl M, Siwy J, Schanstra JP, Mullen W, Koch FH, Kopitz J, Kretz FT, Auffarth GU, Koss MJ.

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion

PLoS One. 2016, 11(6):e0158001.


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341.
Bhat A, Mokou M, Zoidakis J, Jankowski V, Vlahou A, Mischak H.

BcCluster: A Bladder Cancer Database at the Molecular Level
Bladder Cancer. 2016, 7;2(1):65-76.


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340.
Pena MJ, Mischak H, Heerspink HJ.

Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease

Diabetologia. 2016, 59(9):1819-31. Epub 2016 Jun 25.


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339.
Rossing K, Bosselmann HS, Gustafsson F, Zhang ZY, Gu YM, Kuznetsova T, Nkuipou-Kenfack E, Mischak H, Staessen JA, Koeck T, Schou M.

Urinary Proteomics Pilot Study for Biomarker Discovery and Diagnosis in Heart Failure with Reduced Ejection Fraction
PLoS One. 2016, 11(6):e0157167.


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338.
Metzger J, Mullen W, Husi H, Stalmach A, Herget-Rosenthal S, Groesdonk HV, Mischak H, Klingele M.

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study
Crit Care. 2016, 20(1):157.


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337.
Farmakis D, Koeck T, Mullen W, Parissis J, Gogas BD, Nikolaou M, Lekakis J, Mischak H, Filippatos G.

Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates
Eur J Heart Fail. 2016 Jul;18(7):822-9. Epub 2016 May 25.


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336.
Latosinska A, Makridakis M, Frantzi M, Borràs DM, Janssen B, Mullen W, Zoidakis J, Merseburger AS, Jankowski V, Mischak H, Vlahou A.

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings
Sci Rep. 2016, 6:25619.


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335.

von Zur Mühlen C, Koeck T, Schiffer E, Sackmann C, Zürbig P, Hilgendorf I, Reinöhl J, Rivera J, Zirlik A, Hehrlein C, Mischak H, Bode C, Peter K.

Urine proteome analysis as a discovery tool in patients with deep vein thrombosis and pulmonary embolism

Proteomics Clin Appl. 2016, 10(5):574-84.


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334.
Carrick E, Vanmassenhove J, Glorieux G, Metzger J, Dakna M, Pejchinovski M, Jankowski V, Mansoorian B, Husi H, Mullen W, Mischak H, Vanholder R, Van Biesen W.

Development of a MALDI MS-based platform for early detection of acute kidney injury
Proteomics Clin Appl. 2016, 10(7):732-42. Epub 2016 May 17.


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333.
Neisius U, Koeck T, Mischak H, Rossi SH, Olson E, Carty DM, Dymott JA, Dominiczak AF, Berry C, Oldroyd KG, Delles C.

Urine proteomics in the diagnosis of stable angina
BMC Cardiovasc Disord. 2016, 16(1):70.


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332.
Frantzi M, Van Kessel KE, Zwarthoff EC, Marquez M, Rava M, Malats N, Merseburger AS, Katafigiotis I, Stravodimos K, Mullen W, Zoidakis J, Makridakis M, Pejchinovski M, Critselis E, Lichtinghagen R, Brand K, Dakna M, Roubelakis MG, Theodorescu D, Vlahou A, Mischak H, Anagnou NP.

Development and validation of urine-based peptide biomarker panels for detecting bladder cancer in a multi-center study

Clin Cancer Res. 2016, 22(16):4077-86. Epub 2016 Mar 29.


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331.

Chatziharalambous D, Lygirou V, Latosinska A, Stravodimos K, Vlahou A, Jankowski V, Zoidakis J.

Analytical Performance of ELISA Assays in Urine: One More Bottleneck towards Biomarker Validation and Clinical Implementation

PLoS One. 2016, 11(2):e0149471.


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330.
Lindhardt M, Persson F, Currie G, Pontillo C, Beige J, Delles C, von der Leyen H, Mischak H, Navis G, Noutsou M, Ortiz A, Ruggenenti PL, Rychlik I, Spasovski G, Rossing P.

Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial
BMJ Open. 2016, 6(3):e010310.


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329.
Pontillo C, Mischak H.

Urinary biomarkers to predict CKD: is the future in multi-marker panels?
Nephrol Dial Transplant. 2016,31(9):1373-5. Epub 2016 Feb 29.


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328.

Samji S, Small HY, Coley S, Mischak H, Mullen W, Delles C.

OP.LB.02.06: Investigation of urinary peptidome over pregnancy in rodent model of hypertension

Journal of Hypertension 2016, 34(Suppl 2):e80.


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327.

Pejchinovski M, Mischak H, Chapman AB, Kistler AD.

SP026: Urine proteome analysis of ADPKD patients selected by a TKV imaging classification method

Nephrology Dialysis Transplantation 2016, 31(Suppl 1):i95.


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326.

Krochmal M, Cisek K, Fernandes M, Husi H, Jankowski J, Zoidakis J, Vlahou A, Mischak H.

MP266: Development of IgA nephropathy molecular model based on an integrative analysis of −omics data

Nephrology Dialysis Transplantation 2016, 31(Suppl 1):i428–i429.


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325.

Drube J, Zürbig P, Mischak H, Pape L.

Chronic kidney disease can be identified reliably by urinary proteome analysis in children after orthotopic liver transplantation

Pediatric Nephrology 2016, 31(10):1748.


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324.

Pejchinovski M, Siwy J, Metzger J, Mischak H, Jankowski V, Chapman AB, Kistler AD.

SO051 Urine peptide markers predicts ESRD risk in ADPKD and reveal proteolytic pathways involved in progression.
Nephrology Dialysis Transplantation
2016, 31(Suppl. 1):i22.



323.

Markoska K, Pejchinovski M, Pontillo C, Zürbig P, Dakna M, Masin-Spasovska J, Stojceva-Taneva O, Mischak H, Spasovski G

MO024 Urinary peptide biomarkers associated with improvement in eGFR in CKD patients

Nephrology Dialysis and Transplantation 2016, 31(Supp1):i38.


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322.

Marx D, Gwinner W, Mischak H, Caillard S, Moulin B, Olagne J, Mullen W, Metzger J.
O43 - Non-invasive diagnosis of BK virus-associated nephropathy by using the urinary peptidome
Transplant International 2016, 29(Suppl1):11.


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321.

Eickhoff MK, Frimodt-Møller M, Lindhardt MK, Dakna M, Mischak H, Rossing P.

995 - Is urinary proteomics useful to predict retinopathy in type 2 diabetic patients in the DIRECT 2 study?

Diabetologia 2016, 59(Suppl1):S478–S479.


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320.

Sanchez-Niño MD, Valiño-Rivas L, Gonzalez-Lafuente L, Husi H, Fresno M, Sanz A, Mezzano S, Vlahou T, Mischak H, Ortiz A. SP173: MAP3K14 promotes acute kidney injury

Nephrol Dial Transplant 2016, 31(Suppl 1):i144. 


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319.

Currie G, Flynn J, Lindhardt M, Mischak H, Rossing P, Delles C.

P69 Markers of subclinical cardiovascular and renal damage in patients with type 2 diabetes and normoalbuminuria: potential guides to personalised preventative therapy?

Diabetic Medicine 2016, 33:62–63.


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318.

Currie G, Flynn J, Lindhardt M, Mischak H, Rossing P, Delles C.

OP.1D.10: The CKD273 urinary proteomic classifier is not a marker of generalised vascular disease in type 2 diabetic patients with normal renal function

Journal of Hypertension 2016, 34(Suppl 2):e14.


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317.

Sanchez-Niño MD, Valiño-Rivas L, Gonzalez-Lafuente L, Husi H, Fresno M, Sanz A, Mezzano S, Vlahou T, Mischak H, Ortiz A. SP173: MAP3K14 promotes acute kidney injury

Nephrology Dialysis Transplantation 2016; 31(Suppl 1):i144.


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316.
Stepczynska A, Schanstra JP, Mischak H.

Implementation of CE-MS-identified proteome-based biomarker panels in drug development and patient management
Bioanalysis. 2016, 8(5):439-55. Epub 2016 Feb 19.


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315.

Nobl M, Reich M, Dacheva I, Siwy J, Mullen W, Schanstra JP, Choi CY, Kopitz J, Kretz FTA, Auffarth GU, Koch F, Koss MJ.

Proteomics of vitreous in neovascular age-related macular degeneration

Exp Eye Res. 2016, 146:107-117. Epub 2016 Jan 6.


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314.

Jankowska U, Latosinska A, Skupien-Rabian B, Swiderska B, Dziedzicka-Wasylewska M, Kedracka-Krok S.

Optimized procedure of extraction, purification and proteomic analysis of nuclear proteins from mouse brain

J Neurosci Methods. 2016, 261:1-9. Epub 2015 Dec 14.


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313.
Klein J, Bascands JL, Mischak H, Schanstra JP.

The role of urinary peptidomics in kidney disease research
Kidney Int. 2016, 89(3):539-45. Epub 2016 Jan 14.


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312.
Schönemeier B, Metzger J, Klein J, Husi H, Bremer B, Armbrecht N, Dakna M, Schanstra JP, Rosendahl J, Wiegand J, Jäger M, Mullen W, Breuil B, Plentz RR, Lichtinghagen R, Brand K, Kühnel F, Mischak H, Manns MP, Lankisch TO.

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis
Pancreas. 2016 Aug;45(7):1018-26.


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311.
Cisek K, Krochmal M, Klein J, Mischak H.

The application of multi-omics and systems biology to identify therapeutic targets in chronic kidney disease

Nephrol Dial Transplant. 2016, 31(12):2003-2011. Epub 2015 Oct 20.


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