Publications 2017
392.
Siwy J, Zürbig P, Argiles A, Beige J, Haubitz M, Jankowski J, Julian BA, Linde PG, Marx D, Mischak H, Mullen W, Novak J, Ortiz A, Persson F, Pontillo C, Rossing P, Rupprecht H, Schanstra JP, Vlahou A, Vanholder R.
Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis
Nephrol Dial Transplant. 2017, 32(12):2079-2089.
391.
Pejchinovski M, Mischak H.
Clinical Proteomics in Kidney Disease: From Discovery to Clinical Application
Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017, 38(3):39-54.
390.
Magalhães P, Pejchinovski M, Markoska K, Banasik M, Klinger M, Švec-Billá D, Rychlík I, Rroji M, Restivo A, Capasso G, Bob F, Schiller A, Ortiz A, Perez-Gomez MV, Cannata P, Sanchez-Niño MD, Naumovic R, Brkovic V, Polenakovic M, Mullen W, Vlahou A, Zürbig P, Pape L, Ferrario F, Denis C, Spasovski G, Mischak H, Schanstra JP.
Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?
Sci Rep. 2017, 7(1):16915.
389.
Krochmal M, Kontostathi G, Magalhães P, Makridakis M, Klein J, Husi H, Leierer J, Mayer G, Bascands JL, Denis C, Zoidakis J, Zürbig P, Delles C, Schanstra JP, Mischak H, Vlahou A.
Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy
Sci Rep. 2017, 7(1):15160.
388.
Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Charturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.
Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker
Kidney Int Rep. 2017, 2(6):1066-1075.
387.
Torati LS, Migaud H, Doherty MK, Siwy J, Mullen W, Mesquita PEC, Albalat A.Comparative proteome and peptidome analysis of the cephalic fluid secreted by Arapaima gigas (Teleostei: Osteoglossidae) during and outside parental care
PLoS One. 2017, 12(10):e0186692.
386.
Lindhardt M, Persson F, Zürbig P, Stalmach A, Mischak H, de Zeeuw D, Lambers Heerspink H, Klein R, Orchard T, Porta M, Fuller J, Bilous R, Chaturvedi N, Parving HH, Rossing P.
Urinary proteomics predict onset of microalbuminuria in normoalbuminuric type 2 diabetic patients, a sub-study of the DIRECT-Protect 2 study
Nephrol Dial Transplant. 2017, 32(11):1866-1873.
385.
Mary S, Small HY, Siwy J, Mullen W, Giri A, Delles C.
Polymerization-Incompetent Uromodulin in the Pregnant Stroke-Prone Spontaneously Hypertensive Rat
Hypertension. 2017, 69(5):910-918. Epub 2017 Mar 27.
384.
Frantzi M, Vlahou A.
Ten Years of Proteomics in Bladder Cancer: Progress and Future Directions
Bladder Cancer. 2017, 27;3(1):1-18.
383.
Cherney D, Perkins BA, Lytvyn Y, Heerspink H, Rodríguez-Ortiz ME, Mischak H.
The effect of sodium/glucose cotransporter 2 (SGLT2) inhibition on the urinary proteome
PLoS One. 2017, 12(10):e0186910.
382.
Latosinska A, Mokou M, Makridakis M, Mullen W, Zoidakis J, Lygirou V, Frantzi M, Katafigiotis I, Stravodimos K, Hupe MC, Dobrzynski M, Kolch W, Merseburger AS, Mischak H, Roubelakis MG, Vlahou A.
Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention
Oncotarget. 2017, 8(41):69435-69455.
381.
Zhang ZY, Ravassa S, Pejchinovski M, Yang WY, Zürbig P, López B, Wei FF, Thijs L, Jacobs L, González A, Voigt JU, Verhamme P, Kuznetsova T, Díez J, Mischak H, Staessen JA.
A Urinary Fragment of Mucin-1 Subunit α Is a Novel Biomarker Associated With Renal Dysfunction in the General Population
Kidney Int Rep. 2017, 2(5):811-820.
380.
Krochmal M, Cisek K, Filip S, Markoska K, Orange C, Zoidakis J, Gakiopoulou C, Spasovski G, Mischak H, Delles C, Vlahou A, Jankowski J.
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis
Sci Rep. 2017 Aug 22;7(1):9091.
379.
Voigtländer T, Metzger J, Schönemeier B, Jäger M, Mischak H, Manns MP, Lankisch TO.
A combined bile and urine proteomic test for cholangiocarcinoma diagnosis in patients with biliary strictures of unknown origin
United European Gastroenterol J. 2017, 5(5):668-676. Epub 2017 Jan 11.
378.
Zhang ZY, Ravassa S, Nkuipou-Kenfack E, Yang WY, Kerr SM, Koeck T, Campbell A, Kuznetsova T, Mischak H, Padmanabhan S, Dominiczak AF, Delles C, Staessen JA.
Novel Urinary Peptidomic Classifier Predicts Incident Heart Failure
J Am Heart Assoc. 2017, 6(8):e005432.
377.
Pontillo C, Jacobs L, Staessen JA, Schanstra JP, Rossing P, Heerspink HJ, Siwy J, Mullen W, Vlahou A, Mischak H, Vanholder R, Zürbig P, Jankowski J.
A urinary proteome-based classifier for the early detection of decline in glomerular filtration
Nephrol Dial Transplant 2017, 32(9):1510-1516.
376.
Pontillo C, Mischak H.
Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease
Clin Kidney J. 2017, 10(2):192-201. Epub 2017 Mar 29.
375.
Wei R, Gao B, Shih F, Ranger A, Dearth A, Mischak H, Siwy J, Wisniacki N, Petri M, Burkly LC.
Alterations in urinary collagen peptides in lupus nephritis subjects correlate with renal dysfunction and renal histopathology
Nephrol Dial Transplant. 2017, 32(9):1468-1477.
374.
Carleo A, Chorostowska-Wynimko J, Koeck T, Mischak H, Czajkowska-Malinowska M, Rozy A, Welte T, Janciauskiene S.
Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency?
Int J Chron Obstruct Pulmon Dis. 2017, 12:829-837.
373.
Ortiz A, Husi H, Gonzalez-Lafuente L, Valiño-Rivas L, Fresno M, Sanz AB, Mullen W, Albalat A, Mezzano S, Vlahou T, Mischak H, Sanchez-Niño MD.
Mitogen-Activated Protein Kinase 14 Promotes AKI
J Am Soc Nephrol. 2017, 28(3):823-836. Epub 2016 Sep 12.
372.
Pejchinovski M, Siwy J, Metzger J, Dakna M, Mischak H, Klein J, Jankowski V, Bae KT, Chapman AB, Kistler AD.
Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression
Nephrol Dial Transplant. 2017, 32(3):487-497.
371.
Htun NM, Magliano DJ, Zhang ZY, Lyons J, Petit T, Nkuipou-Kenfack E, Ramirez-Torres A, von Zur Muhlen C, Maahs D, Schanstra JP, Pontillo C, Pejchinovski M, Snell-Bergeon JK, Delles C, Mischak H, Staessen JA, Shaw JE, Koeck T, Peter K.
Prediction of acute coronary syndromes by urinary proteome analysis
PLoS One. 2017, 12(3):e0172036.
370.
Zoidakis J, Mokou M, Galaras A, Latosinska A, Lygirou V, Makridakis M, Fragkoulis C, Mullen W, Mischak H, Roubelakis M, Merseburger A, Ntoumas K, Vlahou A.
Proteomics phenotyping of bladder cancer.
Urologic Oncology: Seminars and Original Investigations. 2017;35(10):620–621.
369.
Zhang ZY, Ravassa S, Pejchinovski M, Yang W-Y, Zürbig P, López B, Wei F-F, Thijs L, Jacobs L, González A, Voigt J-U, Verhamme P, Kuznetsova T, Díez J, Mischak H, Staessen JA.
A urinary fragment of mucin 1 subunit alpha is a novel biomarker associated with renal dysfunction in the general population
OMICS as Tool to Address the Burden of Non-Communicable Age-Related Disease in Populations in Epidemiological Transition. Chapter 3.3: Mechanistic studies of proteomic biomarkers, Acta Biomedica Lovaniensia 2017, 11, pp. 377-420.
368.
Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Chaturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.
Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker
OMICS as Tool to Address the Burden of Non-Communicable Age-Related Disease in Populations in Epidemiological Transition. Chapter 2.5: Multidimensional urinary proteomic markers, Acta Biomedica Lovaniensia 2017, 11, pp. 239-270.
367.
Zhang ZY, Thijs L, Petit T, Gu Y, Jacobs L, Yang WY, Liu YP, Koeck T, Zürbig P, Jin Y, Verhamme P, Voigt J-U, Kuznetsova T, Mischak H, Staessen JA.
The urinary proteome and systolic blood pressure as predictors of 5 year cardiovascular and cardiac outcomes in a general population
OMICS as Tool to Address the Burden of Non-Communicable Age-Related Disease in Populations in Epidemiological Transition. Chapter 2.3: Multidimensional urinary proteomic markers, Acta Biomedica Lovaniensia 2017, 11, pp. 161-208.
366.
Zhang ZY, Staessen JA, Thijs L, Gu Y, Liu Y, Jacobs L, Koeck T, Zürbig P, Mischak H, Kuznetsova T.
Left ventricular diastolic function in relation to urinary proteome: a proof-of-concept study in a general population
OMICS as Tool to Address the Burden of Non-Communicable Age-Related Disease in Populations in Epidemiological Transition. Chapter 2.1: Multidimensional urinary proteomic markers, Acta Biomedica Lovaniensia 2017, 11, pp. 47-130.
365.
Zhang ZY, Ravassa S, Yang WY, Petit T, Pejchinovski M, Zürbig P, López B, Wei FF, Pontillo C, Thijs L.
Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population
OMICS as Tool to Address the Burden of Non-Communicable Age-Related Disease in Populations in Epidemiological Transition. Chapter 3.1: Mechanistic studies of proteomic biomarkers, Acta Biomedica Lovaniensia 2017, 11, pp. 271-314.
364.
Drube J, Zürbig P, Beige J, Mischak H, Jankowski J.
Proteomanalyse: Neue Wege zur verbesserten Behandlung der diabetischen Nephropathie.
Diabetologie und Stoffwechsel
2017, 12(3):213–221.
363.
Chorostowska-Wynimko J, Carleo A, Koeck T, Mischak H, Czajkowska-Malinowska M, Rozy A, Welte T, Janciauskiene S.
P1238 Can Urinary Peptides Discriminate Between COPD Patients with and Without Inherited Alpha1-Antitrypsin Deficiency?
Am J Respir Crit Care Med. 2017;195(Suppl 1):A6323.
362.
Torati LS, Migaud H, Doherty MK, Siwy J, Mullen W, Mesquita PEC, Albalat A.
Comparative proteome and peptidome analysis of the cephalic fluid secreted by Arapaima gigas (Teleostei: Osteoglossidae) during and outside parental care
PLoS ONE
2017, 12(10):e0186692.
361.
Chorostowska-Wynimko J, Carleo A, Koeck T, Mischak H, Czajkowska-Malinowska M, Rozy A, Welte T, Janciauskiene S.
P1238 - Can Urinary Peptides Discriminate Between COPD Patients With and Without Inherited Alpha1-Antitrypsin Deficiency?
American Journal of Respiratory and Critical Care Medicine 2017, 195(Suppl1):A6323.
360.
Zhang Z-Y, Izoidakis M, Yang W-Y, Thijs L, Wei F-F, Huang Q-F, Schanstra J, Voigt J-U, Kuznetsova T, Verhamme P, Vlahou A, Mischak H, Staessen J.
P7: The urinary peptidomic signature of aortic stiffness reveals molecular pathways and drug targets
Artery Research 2017, 20(C):63.
359.
Duranton F, Gayrard N, Ficheux A, Lajoix AD, Weinberger KM, Mischak H, Argilés A.
SP270: Plasma lipidomics in chronic kidney disease and hemodialysis patients
Nephrology Dialysis Transplantation 2017, 32(Suppl 3):iii197–iii198.
358.
Currie G, Mary S, von Scholten BJ, Lindhardt MK, Mischak H, Mullen W, Rossing P, Delles C.
1.4: A proteomic marker of diabetic nephropathy is associated with mortality in patients with type 2 diabetes
Artery Research 2017, 20(C):48.
357.
Currie G, Sheon M, von Scholten BJ, Lindhardt M, Mischak H, Mullen W, Rossing P, Delles C.
P142: The CKD273 urinary peptidomic biomarker is associated with mortality in people at early stages of diabetic nephropathy independent of traditional risk factors
Hypertension 2017 70(Suppl 1):AP142.
356.
Nkuipou-Kenfack E, Schanstra JP, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands JL, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber TB, Rudolph KL, Pich A, Mischak H, Zürbig P.
The use of urinary proteomics in the assessment of suitability of mouse models for ageing
PLoS One. 2017, 12(2):e0166875.
355.
Albalat A, Mullen W, Husi H, Mischak H.
Tissue Proteomics in Vascular Disease
Methods Mol Biol. 2017, 1527:53-60.
354.
Siebert S, Porter D, Paterson C, Hampson R, Gaya D, Latosinska A, Mischak H, Schanstra J, Mullen W, McInnes I.
Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups
Sci Rep. 2017, 16;7:40473.
353.
Nkuipou-Kenfack E, Zürbig P, Mischak H.
The long path towards implementation of clinical proteomics: Exemplified based on CKD273
Proteomics Clin Appl. 2017, 11(5-6). Epub 2017 Jan 17.
352.
Mokou M, Lygirou V, Vlahou A, Mischak H.
Proteomics in cardiovascular disease: recent progress and clinical implication and implementation
Expert Rev Proteomics. 2017, 14(2):117-136. Epub 2017 Jan 5.