News | 2019

Project funded by the European Regional Development Fund (ERDF)

Qualitätskontrolle von Blutprodukten (Quality control of blood products)

Identification of markers for quality and stability of blood products using protein pattern, exemplarily demonstrated by the use of serum eye drops.

Pharmaceutical companies that market blood products are bound by a large number of regulations. However, there are no established analytical methods to verify the consistent quality or stability of blood products based on their ingredients. However, as most biological products are subject to their inherent variability, these must be defined by clear limits and strictly controlled by manufacturers and regulators. Since the Paul Ehrlich Institute, the regulatory authority for biological drugs, has recommended human serum for the treatment of dry eyes (Sicca-Syndrome), a quality and stability control is to be developed in this project by means of the proteins in human serum or serum eye drops. This will be performed by the generation of specific protein patterns based on the proteome analysis.


CE-MS-based urinary biomarkers to distinguish non-significant from significant prostate cancer

Mosaiques’ diagnostics study entitled:

CE-MS-based urinary biomarkers to distinguish non-significant from significant prostate cancer”

was awarded in 13. Nordkongress Urologie in Hamburg

13 – 15 June 2019

The study presents a CE-MS based urinary test of 19-peptides that enables detection of significant prostate cancer in patients with low levels of PSA (<15ng/ml) with sensitivity of 90% (AUC=0.81), outperforming PSA (AUC = 0.58) and the ERSPC-3/4 risk calculator (AUC = 0.69)

Please find more information on the Study:

Read more here:


Clinical Proteomics on the Path Toward Implementation: First Promises Delivered

Read the full article here.


15 years collaboration: NBank & mosaiques Group

The collaboration between NBank and Mosaiques Diagnostics could be described as “stories that life wrote”.


Read the full article here.

For further information of the project funded by the NBank see here.