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66: Albalat A, Husi H, Stalmach A, Schanstra JP, Mischak H. Classical MALDI-MS
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67: Klein J, Buffin-Meyer B, Mullen W, Carty DM, Delles C, Vlahou A, Mischak H,
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68: Frantzi M, Metzger J, Banks RE, Husi H, Klein J, Dakna M, Mullen W, Cartledge
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69: Klein J, Papadopoulos T, Mischak H, Mullen W. Comparison of CE-MS/MS and
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70: Duranton F, Lundin U, Gayrard N, Mischak H, Aparicio M, Mourad G, Daurès JP,
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71: Husi H, Sanchez-Niño MD, Delles C, Mullen W, Vlahou A, Ortiz A, Mischak H. A
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72: Dissard R, Klein J, Caubet C, Breuil B, Siwy J, Hoffman J, Sicard L, Ducassé
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73: Latosinska A, Frantzi M, Vlahou A, Mischak H. Clinical applications of
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74: Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B,
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75: Albalat A, Stalmach A, Bitsika V, Siwy J, Schanstra JP, Petropoulos AD,
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76: Frantzi M, Zoidakis J, Papadopoulos T, Zürbig P, Katafigiotis I, Stravodimos
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77: Weissinger EM, Metzger J, Dobbelstein C, Wolff D, Schleuning M, Kuzmina Z,
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78: Klein G, Schanstra JP, Hoffmann J, Mischak H, Siwy J, Zimmermann K.
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79: Rodríguez-Suárez E, Siwy J, Zürbig P, Mischak H. Urine as a source for
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80: Argilés Á, Siwy J, Duranton F, Gayrard N, Dakna M, Lundin U, Osaba L, Delles
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81: Mansor R, Mullen W, Albalat A, Zerefos P, Mischak H, Barrett DC, Biggs A,
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82: Jankowski V, Schulz A, Kretschmer A, Mischak H, Boehringer F, van der Giet M,
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83: Stalmach A, Albalat A, Mullen W, Mischak H. Recent advances in capillary
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84: Klein J, Eales J, Zürbig P, Vlahou A, Mischak H, Stevens R. Proteasix: a tool
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85: Kistler AD, Serra AL, Siwy J, Poster D, Krauer F, Torres VE, Mrug M, Grantham
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86: Siwy J, Zoja C, Klein J, Benigni A, Mullen W, Mayer B, Mischak H, Jankowski
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87: Roscioni SS, de Zeeuw D, Hellemons ME, Mischak H, Zürbig P, Bakker SJ,
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88: Mischak H, Vlahou A, Ioannidis JP. Technical aspects and inter-laboratory
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89: Albalat A, Franke J, Gonzalez J, Mischak H, Zürbig P. Urinary proteomics
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90: Herget-Rosenthal S, Metzger J, Albalat A, Bitsika V, Mischak H. Proteomic
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91: Zürbig P, Jerums G, Hovind P, Macisaac RJ, Mischak H, Nielsen SE,
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92: Molin L, Seraglia R, Lapolla A, Ragazzi E, Gonzalez J, Vlahou A, Schanstra
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93: Mischak H. How to get proteomics to the clinic? Issues in clinical
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94: Kuznetsova T, Mischak H, Mullen W, Staessen JA. Urinary proteome analysis in
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96: Dawson J, Walters M, Delles C, Mischak H, Mullen W. Urinary proteomics to
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97: Metzger J, Negm AA, Plentz RR, Weismüller TJ, Wedemeyer J, Karlsen TH, Dakna
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98: Mischak H, Ioannidis JP, Argiles A, Attwood TK, Bongcam-Rudloff E, Broenstrup
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99: Rouse R, Siwy J, Mullen W, Mischak H, Metzger J, Hanig J. Proteomic candidate
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100: Mullen W, Albalat A, Gonzalez J, Zerefos P, Siwy J, Franke J, Mischak H.
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101: von zur Muhlen C, Schiffer E, Sackmann C, Zürbig P, Neudorfer I, Zirlik A,
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102: Drube J, Schiffer E, Lau E, Petersen C, Kirschstein M, Kemper MJ,
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103: Bandin F, Siwy J, Breuil B, Mischak H, Bascands JL, Decramer S, Schanstra
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104: Mullen W, Gonzalez J, Siwy J, Franke J, Sattar N, Mullan A, Roberts S,
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105: Jahn H, Wittke S, Zürbig P, Raedler TJ, Arlt S, Kellmann M, Mullen W,
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106: Albalat A, Mischak H, Mullen W. Clinical application of urinary
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107: Mullen W, Delles C, Mischak H; EuroKUP COST action. Urinary proteomics in
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108: Albalat A, Mischak H, Mullen W. Urine proteomics in clinical applications:
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109: Kistler AD, Siwy J, Breunig F, Jeevaratnam P, Scherl A, Mullen W, Warnock
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110: Mischak H, Thongboonkerd V, Schanstra JP, Vlahou A. Renal and urinary
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111: Metzger J, Chatzikyrkou C, Broecker V, Schiffer E, Jaensch L, Iphoefer A,
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112: Lankisch TO, Metzger J, Negm AA, Vosskuhl K, Schiffer E, Siwy J, Weismüller
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113: Mayer G, Heinze G, Mischak H, Hellemons ME, Heerspink HJ, Bakker SJ, de
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114: Foucher C, Schiffer E, Mischak H, Ansquer JC, Wilbraham D. Effect of
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115: Schiffer E, Liabeuf S, Lacroix C, Temmar M, Renard C, Monsarrat B, Choukroun
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116: Mischak H, Schanstra JP. CE-MS in biomarker discovery, validation, and
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117: Dakna M, Harris K, Kalousis A, Carpentier S, Kolch W, Schanstra JP, Haubitz
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118: Carty DM, Siwy J, Brennand JE, Zürbig P, Mullen W, Franke J, McCulloch JW,
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119: Mischak H, Kolch W, Aivaliotis M, Bouyssié D, Court M, Dihazi H, Dihazi GH,
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121: Andersen S, Mischak H, Zürbig P, Parving HH, Rossing P. Urinary proteome
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122: Alkhalaf A, Zürbig P, Bakker SJ, Bilo HJ, Cerna M, Fischer C, Fuchs S,
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124: Metzger J, Kirsch T, Schiffer E, Ulger P, Mentes E, Brand K, Weissinger EM,
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126: Mischak H, Allmaier G, Apweiler R, Attwood T, Baumann M, Benigni A, Bennett
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129: Griner EM, Caino MC, Sosa MS, Colón-González F, Chalmers MJ, Mischak H,
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131: Mischak H, Espandiari P, Sadrieh N, Hanig J. Profiling of rat urinary
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135: Caubet C, Lacroix C, Decramer S, Drube J, Ehrich JH, Mischak H, Bascands JL,
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136: Schiffer E, Vlahou A, Petrolekas A, Stravodimos K, Tauber R, Geschwend JE,
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137: Dhillon AS, Yip YY, Grindlay GJ, Pakay JL, Dangers M, Hillmann M, Clark W,
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141: Weissinger EM, Mischak H, Kontsendorn J, Hahn A, Hahn N, Morgan M, Ganser A.
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143: Kistler AD, Mischak H, Poster D, Dakna M, Wüthrich RP, Serra AL.
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144: Zürbig P, Decramer S, Dakna M, Jantos J, Good DM, Coon JJ, Bandin F, Mischak
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145: Drube J, Schiffer E, Mischak H, Kemper MJ, Neuhaus T, Pape L, Lichtinghagen
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146: Schiffer E, Mischak H, Zimmerli LU. Proteomics in gerontology: current
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147: Snell-Bergeon JK, Maahs DM, Ogden LG, Kinney GL, Hokanson JE, Schiffer E,
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148: von Zur Muhlen C, Schiffer E, Zuerbig P, Kellmann M, Brasse M, Meert N,
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149: Jantos-Siwy J, Schiffer E, Brand K, Schumann G, Rossing K, Delles C, Mischak
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150: Dakna M, He Z, Yu WC, Mischak H, Kolch W. Technical, bioinformatical and
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152: Metzger J, Schanstra JP, Mischak H. Capillary electrophoresis-mass
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154: Decramer S, Gonzalez de Peredo A, Breuil B, Mischak H, Monsarrat B, Bascands
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155: Vlahou A, Schanstra J, Frokiaer J, El Nahas M, Spasovski G, Mischak H, Domon
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156: Coon JJ, Zürbig P, Dakna M, Dominiczak AF, Decramer S, Fliser D, Frommberger
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157: Rossing K, Mischak H, Rossing P, Schanstra JP, Wiseman A, Maahs DM. The
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160: Decramer S, Zürbig P, Wittke S, Mischak H, Bascands JL, Schanstra JP.
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162: Theodorescu D, Schiffer E, Bauer HW, Douwes F, Eichhorn F, Polley R, Schmidt
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165: Schiffer E, Mischak H, Theodorescu D, Vlahou A. Challenges of using mass
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166: Raedler TJ, Wittke S, Jahn H, Koessler A, Mischak H, Wiedemann K. Capillary
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167: Goodsaid F, Bandow JE, Mischak H. Grand rounds in proteomics at the FDA
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168: Julian BA, Wittke S, Novak J, Good DM, Coon JJ, Kellmann M, Zürbig P,
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169: Good DM, Thongboonkerd V, Novak J, Bascands JL, Schanstra JP, Coon JJ,
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170: Zimmerli LU, Schiffer E, Zürbig P, Good DM, Kellmann M, Mouls L, Pitt AR,
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171: Theodorescu D, Mischak H. Mass spectrometry based proteomics in urine
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172: Weissinger EM, Mischak H. Application of proteomics to posttransplantational
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173: Mischak H, Julian BA, Novak J. High-resolution proteome/peptidome analysis
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174: Frommberger M, Zürbig P, Jantos J, Krahn T, Mischak H, Pich A, Just I,
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175: Vanholder R, Meert N, Schepers E, Glorieux G, Argiles A, Brunet P, Cohen G,
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176: Sniehotta M, Schiffer E, Zürbig P, Novak J, Mischak H. CE - a
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177: Fliser D, Novak J, Thongboonkerd V, Argilés A, Jankowski V, Girolami MA,
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178: Mischak H, Apweiler R, Banks RE, Conaway M, Coon J, Dominiczak A, Ehrich JH,
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179: Schiffer E, Mischak H, Novak J. High resolution proteome/peptidome analysis
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180: Zürbig P, Renfrow MB, Schiffer E, Novak J, Walden M, Wittke S, Just I,
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181: Girolami M, Mischak H, Krebs R. Analysis of complex, multidimensional
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182: Decramer S, Wittke S, Mischak H, Zürbig P, Walden M, Bouissou F, Bascands
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183: Theodorescu D, Wittke S, Ross MM, Walden M, Conaway M, Just I, Mischak H,
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184: Weissinger EM, Mischak H, Ganser A, Hertenstein B. Value of proteomics
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185: Weissinger EM, Nguyen-Khoa T, Fumeron C, Saltiel C, Walden M, Kaiser T,
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186: Chalmers MJ, Mackay CL, Hendrickson CL, Wittke S, Walden M, Mischak H,
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187: Weissinger EM, Hertenstein B, Mischak H, Ganser A. Online coupling of
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188: Wittke S, Haubitz M, Walden M, Rohde F, Schwarz A, Mengel M, Mischak H,
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189: Meier M, Kaiser T, Herrmann A, Knueppel S, Hillmann M, Koester P, Danne T,
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190: Theodorescu D, Fliser D, Wittke S, Mischak H, Krebs R, Walden M, Ross M,
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191: Fliser D, Wittke S, Mischak H. Capillary electrophoresis coupled to mass
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192: Rossing K, Mischak H, Parving HH, Christensen PK, Walden M, Hillmann M,
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193: Haubitz M, Wittke S, Weissinger EM, Walden M, Rupprecht HD, Floege J, Haller
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194: Kolch W, Mischak H, Pitt AR. The molecular make-up of a tumour: proteomics
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195: Wittke S, Mischak H, Walden M, Kolch W, Rädler T, Wiedemann K. Discovery of
biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis
coupled to mass spectrometry: towards new diagnostic and therapeutic approaches.
Electrophoresis. 2005 Apr;26(7-8):1476-87. PubMed PMID: 15765478.

196: Kolch W, Neusüss C, Pelzing M, Mischak H. Capillary electrophoresis-mass
spectrometry as a powerful tool in clinical diagnosis and biomarker discovery.
Mass Spectrom Rev. 2005 Nov-Dec;24(6):959-77. Review. PubMed PMID: 15747373.

197: Canagarajah B, Leskow FC, Ho JY, Mischak H, Saidi LF, Kazanietz MG, Hurley
JH. Structural mechanism for lipid activation of the Rac-specific GAP,
beta2-chimaerin. Cell. 2004 Oct 29;119(3):407-18. PubMed PMID: 15507211.

198: Weissinger EM, Kaiser T, Meert N, De Smet R, Walden M, Mischak H, Vanholder
RC. Proteomics: a novel tool to unravel the patho-physiology of uraemia. Nephrol
Dial Transplant. 2004 Dec;19(12):3068-77. Epub 2004 Oct 19. PubMed PMID:
15494356.

199: Kolch W, Mischak H, Chalmers MJ, Pitt A, Marshall AG. Clinical proteomics: a
question of technology. Rapid Commun Mass Spectrom. 2004;18(19):2365-6. PubMed
PMID: 15384161.

200: Mischak H, Kaiser T, Walden M, Hillmann M, Wittke S, Herrmann A, Knueppel S,
Haller H, Fliser D. Proteomic analysis for the assessment of diabetic renal
damage in humans. Clin Sci (Lond). 2004 Nov;107(5):485-95. PubMed PMID: 15281910.

201: Schaefer M, Mischak H, Schnell S, Griese A, Iakubov R, Riepenhausen G,
Schöfl C. Mechanisms of arginine-vasopressin-induced Ca2+ oscillations in
beta-cells (HIT-T15): a role for oscillating protein kinase C. Endocrinology.
2004 Oct;145(10):4635-44. Epub 2004 Jul 8. PubMed PMID: 15242987.

202: Kaiser T, Wittke S, Just I, Krebs R, Bartel S, Fliser D, Mischak H,
Weissinger EM. Capillary electrophoresis coupled to mass spectrometer for
automated and robust polypeptide determination in body fluids for clinical use.
Electrophoresis. 2004 Jul;25(13):2044-55. PubMed PMID: 15237405.

203: Weissinger EM, Oettrich K, Evans C, Genieser HG, Schwede F, Dangers M,
Dammann E, Kolb HJ, Mischak H, Ganser A, Kolch W. Activation of protein kinase A
(PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy. Br J Cancer.
2004 Jul 5;91(1):186-92. PubMed PMID: 15188002; PubMed Central PMCID: PMC2364761.

204: Weissinger EM, Wittke S, Kaiser T, Haller H, Bartel S, Krebs R, Golovko I,
Rupprecht HD, Haubitz M, Hecker H, Mischak H, Fliser D. Proteomic patterns
established with capillary electrophoresis and mass spectrometry for diagnostic
purposes. Kidney Int. 2004 Jun;65(6):2426-34. PubMed PMID: 15149356.

205: Kaiser T, Kamal H, Rank A, Kolb HJ, Holler E, Ganser A, Hertenstein B,
Mischak H, Weissinger EM. Proteomics applied to the clinical follow-up of
patients after allogeneic hematopoietic stem cell transplantation. Blood. 2004
Jul 15;104(2):340-9. Epub 2004 Mar 30. PubMed PMID: 15054046.

206: Chalmers MJ, Kolch W, Emmett MR, Marshall AG, Mischak H. Identification and
analysis of phosphopeptides. J Chromatogr B Analyt Technol Biomed Life Sci. 2004
Apr 15;803(1):111-20. Review. PubMed PMID: 15026004.

207: Wittke S, Kaiser T, Mischak H. Differential polypeptide display: the search
for the elusive target. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr
15;803(1):17-26. Review. PubMed PMID: 15025995.

208: Wang QJ, Lu G, Schlapkohl WA, Goerke A, Larsson C, Mischak H, Blumberg PM,
Mushinski JF. The V5 domain of protein kinase C plays a critical role in
determining the isoform-specific localization, translocation, and biological
function of protein kinase C-delta and -epsilon. Mol Cancer Res. 2004
Feb;2(2):129-40. PubMed PMID: 14985469.

209: Neuhoff Nv, Kaiser T, Wittke S, Krebs R, Pitt A, Burchard A, Sundmacher A,
Schlegelberger B, Kolch W, Mischak H. Mass spectrometry for the detection of
differentially expressed proteins: a comparison of surface-enhanced laser
desorption/ionization and capillary electrophoresis/mass spectrometry. Rapid
Commun Mass Spectrom. 2004;18(2):149-56. PubMed PMID: 14745763.

210: Wittke S, Fliser D, Haubitz M, Bartel S, Krebs R, Hausadel F, Hillmann M,
Golovko I, Koester P, Haller H, Kaiser T, Mischak H, Weissinger EM. Determination
of peptides and proteins in human urine with capillary electrophoresis-mass
spectrometry, a suitable tool for the establishment of new diagnostic markers. J
Chromatogr A. 2003 Sep 26;1013(1-2):173-81. PubMed PMID: 14604118.

211: Kaiser T, Hermann A, Kielstein JT, Wittke S, Bartel S, Krebs R, Hausadel F,
Hillmann M, Golovko I, Koester P, Haller H, Weissinger EM, Fliser D, Mischak H.
Capillary electrophoresis coupled to mass spectrometry to establish polypeptide
patterns in dialysis fluids. J Chromatogr A. 2003 Sep 26;1013(1-2):157-71. PubMed
PMID: 14604117.

212: Chalmers MJ, Quinn JP, Blakney GT, Emmett MR, Mischak H, Gaskell SJ,
Marshall AG. Liquid chromatography-Fourier transform ion cyclotron resonance mass
spectrometric characterization of protein kinase C phosphorylation. J Proteome
Res. 2003 Jul-Aug;2(4):373-82. PubMed PMID: 12938927.

213: Brandt DT, Goerke A, Heuer M, Gimona M, Leitges M, Kremmer E, Lammers R,
Haller H, Mischak H. Protein kinase C delta induces Src kinase activity via
activation of the protein tyrosine phosphatase PTP alpha. J Biol Chem. 2003 Sep
5;278(36):34073-8. Epub 2003 Jun 25. PubMed PMID: 12826681.

214: Eitel K, Staiger H, Rieger J, Mischak H, Brandhorst H, Brendel MD, Bretzel
RG, Häring HU, Kellerer M. Protein kinase C delta activation and translocation to
the nucleus are required for fatty acid-induced apoptosis of insulin-secreting
cells. Diabetes. 2003 Apr;52(4):991-7. PubMed PMID: 12663471.

215: Dhillon AS, Meikle S, Peyssonnaux C, Grindlay J, Kaiser C, Steen H, Shaw PE,
Mischak H, Eychène A, Kolch W. A Raf-1 mutant that dissociates MEK/extracellular
signal-regulated kinase activation from malignant transformation and
differentiation but not proliferation. Mol Cell Biol. 2003 Mar;23(6):1983-93.
PubMed PMID: 12612072; PubMed Central PMCID: PMC149463.

216: Goerke A, Sakai N, Gutjahr E, Schlapkohl WA, Mushinski JF, Haller H, Kolch
W, Saito N, Mischak H. Induction of apoptosis by protein kinase C delta is
independent of its kinase activity. J Biol Chem. 2002 Aug 30;277(35):32054-62.
Epub 2002 Jun 7. PubMed PMID: 12055197.

217: Dhillon AS, Pollock C, Steen H, Shaw PE, Mischak H, Kolch W. Cyclic
AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine
259. Mol Cell Biol. 2002 May;22(10):3237-46. PubMed PMID: 11971957; PubMed
Central PMCID: PMC133783.

218: Brandt D, Gimona M, Hillmann M, Haller H, Mischak H. Protein kinase C
induces actin reorganization via a Src- and Rho-dependent pathway. J Biol Chem.
2002 Jun 7;277(23):20903-10. Epub 2002 Mar 29. PubMed PMID: 11925438.

219: Walter R, Mischak H, Haller H. Haemodialysis, atherosclerosis and
inflammation-identifying molecular mechanisms of chronic vascular disease in ESDR
patients. Nephrol Dial Transplant. 2002;17 Suppl 3:24-9. Review. PubMed PMID:
11912296.

220: Hennige AM, Fritsche A, Strack V, Weigert C, Mischak H, Borboni P, Renn W,
Häring HU, Kellerer M. PKC zeta enhances insulin-like growth factor 1-dependent
mitogenic activity in the rat clonal beta cell line RIN 1046-38. Biochem Biophys
Res Commun. 2002 Jan 11;290(1):85-90. PubMed PMID: 11779137.

221: Krasel C, Dammeier S, Winstel R, Brockmann J, Mischak H, Lohse MJ.
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by
calmodulin. J Biol Chem. 2001 Jan 19;276(3):1911-5. Epub 2000 Oct 19. PubMed
PMID: 11042191.

222: Janosch P, Kieser A, Eulitz M, Lovric J, Sauer G, Reichert M, Gounari F,
Büscher D, Baccarini M, Mischak H, Kolch W. The Raf-1 kinase associates with
vimentin kinases and regulates the structure of vimentin filaments. FASEB J. 2000
Oct;14(13):2008-21. PubMed PMID: 11023985.

223: Dammeier S, Lovric J, Eulitz M, Kolch W, Mushinski JF, Mischak H.
Identification of the smooth muscle-specific protein, sm22, as a novel protein
kinase C substrate using two-dimensional gel electrophoresis and mass
spectrometry. Electrophoresis. 2000 Jul;21(12):2443-53. PubMed PMID: 10939458.

224: Mai S, Hanley-Hyde J, Rainey GJ, Kuschak TI, Paul JT, Littlewood TD, Mischak
H, Stevens LM, Henderson DW, Mushinski JF. Chromosomal and extrachromosomal
instability of the cyclin D2 gene is induced by Myc overexpression. Neoplasia.
1999 Aug;1(3):241-52. PubMed PMID: 10935479; PubMed Central PMCID: PMC1508077.

225: Baumann M, Gires O, Kolch W, Mischak H, Zeidler R, Pich D, Hammerschmidt W.
The PKC targeting protein RACK1 interacts with the Epstein-Barr virus activator
protein BZLF1. Eur J Biochem. 2000 Jun;267(12):3891-901. PubMed PMID: 10849009.

226: Abraham D, Podar K, Pacher M, Kubicek M, Welzel N, Hemmings BA, Dilworth SM,
Mischak H, Kolch W, Baccarini M. Raf-1-associated protein phosphatase 2A as a
positive regulator of kinase activation. J Biol Chem. 2000 Jul
21;275(29):22300-4. PubMed PMID: 10801873.

227: Yeung K, Janosch P, McFerran B, Rose DW, Mischak H, Sedivy JM, Kolch W.
Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase
pathway by the raf kinase inhibitor protein. Mol Cell Biol. 2000
May;20(9):3079-85. PubMed PMID: 10757792; PubMed Central PMCID: PMC85596.

228: Häcker H, Mischak H, Häcker G, Eser S, Prenzel N, Ullrich A, Wagner H. Cell
type-specific activation of mitogen-activated protein kinases by CpG-DNA controls
interleukin-12 release from antigen-presenting cells. EMBO J. 1999 Dec
15;18(24):6973-82. PubMed PMID: 10601019; PubMed Central PMCID: PMC1171760.

229: Cooper DR, Watson JE, Patel N, Illingworth P, Acevedo-Duncan M, Goodnight J,
Chalfant CE, Mischak H. Ectopic expression of protein kinase CbetaII, -delta, and
-epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose
uptake in NIH-3T3 cells. Arch Biochem Biophys. 1999 Dec 1;372(1):69-79. Erratum
in: Arch Biochem Biophys 2001 Apr 1;388(1):178. PubMed PMID: 10562418.

230: Caloca MJ, Garcia-Bermejo ML, Blumberg PM, Lewin NE, Kremmer E, Mischak H,
Wang S, Nacro K, Bienfait B, Marquez VE, Kazanietz MG. beta2-chimaerin is a novel
target for diacylglycerol: binding properties and changes in subcellular
localization mediated by ligand binding to its C1 domain. Proc Natl Acad Sci U S
A. 1999 Oct 12;96(21):11854-9. PubMed PMID: 10518540; PubMed Central PMCID:
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231: Yeung K, Seitz T, Li S, Janosch P, McFerran B, Kaiser C, Fee F, Katsanakis
KD, Rose DW, Mischak H, Sedivy JM, Kolch W. Suppression of Raf-1 kinase activity
and MAP kinase signalling by RKIP. Nature. 1999 Sep 9;401(6749):173-7. PubMed
PMID: 10490027.

232: Häcker H, Mischak H, Miethke T, Liptay S, Schmid R, Sparwasser T, Heeg K,
Lipford GB, Wagner H. CpG-DNA-specific activation of antigen-presenting cells
requires stress kinase activity and is preceded by non-specific endocytosis and
endosomal maturation. EMBO J. 1998 Nov 2;17(21):6230-40. PubMed PMID: 9799232;
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233: Baumann M, Mischak H, Dammeier S, Kolch W, Gires O, Pich D, Zeidler R,
Delecluse HJ, Hammerschmidt W. Activation of the Epstein-Barr virus transcription
factor BZLF1 by 12-O-tetradecanoylphorbol-13-acetate-induced phosphorylation. J
Virol. 1998 Oct;72(10):8105-14. PubMed PMID: 9733851; PubMed Central PMCID:
PMC110148.

234: Lovrić J, Dammeier S, Kieser A, Mischak H, Kolch W. Activated raf induces
the hyperphosphorylation of stathmin and the reorganization of the microtubule
network. J Biol Chem. 1998 Aug 28;273(35):22848-55. PubMed PMID: 9712920.

235: Kellerer M, Mushack J, Seffer E, Mischak H, Ullrich A, Häring HU. Protein
kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to
inhibit the tyrosine kinase activity of the insulin receptor in human kidney
embryonic cells (HEK 293 cells). Diabetologia. 1998 Jul;41(7):833-8. PubMed PMID:
9686926.

236: Wooten MW, Seibenhener ML, Heikkila JE, Mischak H. Delta-protein kinase C
phosphorylation parallels inhibition of nerve growth factor-induced
differentiation independent of changes in Trk A and MAP kinase signalling in PC12
cells. Cell Signal. 1998 Apr;10(4):265-76. PubMed PMID: 9617484.

237: Maucher C, Weissinger EM, Kremmer E, Baccarini M, Procyk K, Henderson DW,
Wolff L, Kolch W, Kaspers B, Mushinski JF, Mischak H. Activation of bcl-2
suppressible 40 and 44 kDa p38-like kinases during apoptosis of early and late B
lymphocytic cell lines. FEBS Lett. 1998 May 1;427(1):29-35. PubMed PMID: 9613594.

238: Prouty SM, Maroo A, Maucher C, Mischak H, Kolch W, Sedivy JM. Studies of
perinuclear and nuclear translocation of the Raf-1 protein in rodent fibroblasts.
Biochim Biophys Acta. 1998 Mar 12;1402(1):6-16. PubMed PMID: 9551081.

239: Müller G, Storz P, Bourteele S, Döppler H, Pfizenmaier K, Mischak H, Philipp
A, Kaiser C, Kolch W. Regulation of Raf-1 kinase by TNF via its second messenger
ceramide and cross-talk with mitogenic signalling. EMBO J. 1998 Feb
2;17(3):732-42. PubMed PMID: 9450998; PubMed Central PMCID: PMC1170422.

240: Wang QJ, Acs P, Goodnight J, Blumberg PM, Mischak H, Mushinski JF. The
catalytic domain of PKC-epsilon, in reciprocal PKC-delta and -epsilon chimeras,
is responsible for conferring tumorgenicity to NIH3T3 cells, whereas both
regulatory and catalytic domains of PKC-epsilon contribute to in vitro
transformation. Oncogene. 1998 Jan 8;16(1):53-60. PubMed PMID: 9467942.

241: Ueffing M, Lovrić J, Philipp A, Mischak H, Kolch W. Protein kinase C-epsilon
associates with the Raf-1 kinase and induces the production of growth factors
that stimulate Raf-1 activity. Oncogene. 1997 Dec 11;15(24):2921-7. PubMed PMID:
9416835.

242: Kellerer M, Mushack J, Mischak H, Häring HU. Protein kinase C (PKC) epsilon
enhances the inhibitory effect of TNF alpha on insulin signaling in HEK293 cells.
FEBS Lett. 1997 Nov 24;418(1-2):119-22. PubMed PMID: 9414108.

243: Bossenmaier B, Mosthaf L, Mischak H, Ullrich A, Häring HU. Protein kinase C
isoforms beta 1 and beta 2 inhibit the tyrosine kinase activity of the insulin
receptor. Diabetologia. 1997 Jul;40(7):863-6. PubMed PMID: 9243110.

244: Weissinger EM, Eissner G, Grammer C, Fackler S, Haefner B, Yoon LS, Lu KS,
Bazarov A, Sedivy JM, Mischak H, Kolch W. Inhibition of the Raf-1 kinase by
cyclic AMP agonists causes apoptosis of v-abl-transformed cells. Mol Cell Biol.
1997 Jun;17(6):3229-41. PubMed PMID: 9154822; PubMed Central PMCID: PMC232176.

245: Wang QJ, Acs P, Goodnight J, Giese T, Blumberg PM, Mischak H, Mushinski JF.
The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon
chimeras mediates phorbol ester-induced macrophage differentiation of mouse
promyelocytes. J Biol Chem. 1997 Jan 3;272(1):76-82. PubMed PMID: 8995230.

246: Mischak H, Seitz T, Janosch P, Eulitz M, Steen H, Schellerer M, Philipp A,
Kolch W. Negative regulation of Raf-1 by phosphorylation of serine 621. Mol Cell
Biol. 1996 Oct;16(10):5409-18. PubMed PMID: 8816453; PubMed Central PMCID:
PMC231540.

247: Kolch W, Philipp A, Mischak H, Dutil EM, Mullen TM, Feramisco JR, Meinkoth
JL, Rose DW. Inhibition of Raf-1 signaling by a monoclonal antibody, which
interferes with Raf-1 activation and with Mek substrate binding. Oncogene. 1996
Sep 19;13(6):1305-14. PubMed PMID: 8808705.

248: Kieser A, Seitz T, Adler HS, Coffer P, Kremmer E, Crespo P, Gutkind JS,
Henderson DW, Mushinski JF, Kolch W, Mischak H. Protein kinase C-zeta reverts
v-raf transformation of NIH-3T3 cells. Genes Dev. 1996 Jun 15;10(12):1455-66.
PubMed PMID: 8666230.

249: Janosch P, Schellerer M, Seitz T, Reim P, Eulitz M, Brielmeier M, Kölch W,
Sedivy JM, Mischak H. Characterization of IkappaB kinases. IkappaB-alpha is not
phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II
substrate. J Biol Chem. 1996 Jun 7;271(23):13868-74. PubMed PMID: 8662925.

250: Perletti GP, Folini M, Lin HC, Mischak H, Piccinini F, Tashjian AH Jr.
Overexpression of protein kinase C epsilon is oncogenic in rat colonic epithelial
cells. Oncogene. 1996 Feb 15;12(4):847-54. PubMed PMID: 8632907.

251: Morawetz R, Lendenfeld T, Mischak H, Mühlbauer M, Gruber F, Goodnight J, de
Graaff LH, Visser J, Mushinski JF, Kubicek CP. Cloning and characterisation of
genes (pkc1 and pkcA) encoding protein kinase C homologues from Trichoderma
reesei and Aspergillus niger. Mol Gen Genet. 1996 Jan 15;250(1):17-28. PubMed
PMID: 8569684.

252: Kieser A, Goodnight J, Kölch W, Mischak H, Mushinski JF. Identification of
the primary growth response gene, ST2/T1, as a gene whose expression is
differentially regulated by different protein kinase C isozymes. FEBS Lett. 1995
Sep 25;372(2-3):189-93. PubMed PMID: 7556667.

253: Crespo P, Mischak H, Gutkind JS. Overexpression of mammalian protein kinase
C-zeta does not affect the growth characteristics of NIH 3T3 cells. Biochem
Biophys Res Commun. 1995 Aug 4;213(1):266-72. PubMed PMID: 7639744.

254: Chalfant CE, Mischak H, Watson JE, Winkler BC, Goodnight J, Farese RV,
Cooper DR. Regulation of alternative splicing of protein kinase C beta by
insulin. J Biol Chem. 1995 Jun 2;270(22):13326-32. PubMed PMID: 7768933.

255: Avignon A, Standaert ML, Yamada K, Mischak H, Spencer B, Farese RV. Insulin
increases mRNA levels of protein kinase C-alpha and -beta in rat adipocytes and
protein kinase C-alpha, -beta and -theta in rat skeletal muscle. Biochem J. 1995
May 15;308 ( Pt 1):181-7. PubMed PMID: 7755564; PubMed Central PMCID: PMC1136861.

256: Goodnight JA, Mischak H, Kolch W, Mushinski JF. Immunocytochemical
localization of eight protein kinase C isozymes overexpressed in NIH 3T3
fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic
reticulum, and nuclear and cell membranes. J Biol Chem. 1995 Apr
28;270(17):9991-10001. PubMed PMID: 7730383.

257: Li S, Janosch P, Tanji M, Rosenfeld GC, Waymire JC, Mischak H, Kolch W,
Sedivy JM. Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins.
EMBO J. 1995 Feb 15;14(4):685-96. PubMed PMID: 7882972; PubMed Central PMCID:
PMC398132.

258: Goodnight J, Mischak H, Mushinski JF. Association of elevated levels of
protein kinase C-zeta mRNA and protein with murine B-lymphocytic neoplasia. Mol
Carcinog. 1994 Nov;11(3):131-7. PubMed PMID: 7945801.

259: Eissner G, Kölch W, Mischak H, Bornkamm GW, Holler E. Differential role of
protein kinase C in cytokine induced lymphocyte-endothelium interaction in vitro.
Scand J Immunol. 1994 Oct;40(4):395-402. PubMed PMID: 7939411.

260: Häfner S, Adler HS, Mischak H, Janosch P, Heidecker G, Wolfman A, Pippig S,
Lohse M, Ueffing M, Kolch W. Mechanism of inhibition of Raf-1 by protein kinase
A. Mol Cell Biol. 1994 Oct;14(10):6696-703. PubMed PMID: 7935389; PubMed Central
PMCID: PMC359200.

261: Morawetz R, Mischak H, Goodnight J, Lendenfeld T, Mushinsky JF, Kubicek CP.
A protein kinase-encoding gene, pkt1, from Trichoderma reesei, homologous to the
yeast YPK1 and YPK2 (YKR2) genes. Gene. 1994 Sep 2;146(2):309-10. PubMed PMID:
8076837.

262: Yamada K, Standaert ML, Yu B, Mischak H, Cooper DR, Farese RV. Insulin-like
effects of sodium orthovanadate on diacylglycerol-protein kinase C signaling in
BC3H-1 myocytes. Arch Biochem Biophys. 1994 Jul;312(1):167-72. PubMed PMID:
8031124.

263: Farese RV, Standaert ML, Arnold TP, Yamada K, Musunuru K, Hernandez H,
Mischak H, Cooper DR. Preferential activation of microsomal
diacylglycerol/protein kinase C signaling during glucose treatment (De Novo
phospholipid synthesis) of rat adipocytes. J Clin Invest. 1994 May;93(5):1894-9.
PubMed PMID: 8182122; PubMed Central PMCID: PMC294296.

264: Kazanietz MG, Bustelo XR, Barbacid M, Kolch W, Mischak H, Wong G, Pettit GR,
Bruns JD, Blumberg PM. Zinc finger domains and phorbol ester pharmacophore.
Analysis of binding to mutated form of protein kinase C zeta and the vav and
c-raf proto-oncogene products. J Biol Chem. 1994 Apr 15;269(15):11590-4. PubMed
PMID: 8157692.

265: Lehel C, Olah Z, Mischak H, Mushinski JF, Anderson WB. Overexpressed protein
kinase C-delta and -epsilon subtypes in NIH 3T3 cells exhibit differential
subcellular localization and differential regulation of sodium-dependent
phosphate uptake. J Biol Chem. 1994 Feb 18;269(7):4761-6. PubMed PMID: 8106444.

266: Li W, Mischak H, Yu JC, Wang LM, Mushinski JF, Heidaran MA, Pierce JH.
Tyrosine phosphorylation of protein kinase C-delta in response to its activation.
J Biol Chem. 1994 Jan 28;269(4):2349-52. PubMed PMID: 7507923.

267: Weissinger EM, Henderson DW, Mischak H, Goodnight J, Mushinski JF. Induction
of plasmacytomas that secrete monoclonal anti-peptide antibodies by retroviral
transformation. J Immunol Methods. 1994 Jan 12;168(1):123-30. PubMed PMID:
8288888.

268: Huppi K, Siwarski D, Goodnight J, Mischak H. Assignment of the protein
kinase C delta polypeptide gene (PRKCD) to human chromosome 3 and mouse
chromosome 14. Genomics. 1994 Jan 1;19(1):161-2. PubMed PMID: 8188219.

269: Goodnight J, Mischak H, Mushinski JF. Selective involvement of protein
kinase C isozymes in differentiation and neoplastic transformation. Adv Cancer
Res. 1994;64:159-209. Review. PubMed PMID: 7879658.

270: Arnold TP, Standaert ML, Hernandez H, Watson J, Mischak H, Kazanietz MG,
Zhao L, Cooper DR, Farese RV. Effects of insulin and phorbol esters on MARCKS
(myristoylated alanine-rich C-kinase substrate) phosphorylation (and other
parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle
and BC3H-1 myocytes. Biochem J. 1993 Oct 1;295 ( Pt 1):155-64. PubMed PMID:
8216211; PubMed Central PMCID: PMC1134832.

271: Mischak H, Pierce JH, Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF.
Phorbol ester-induced myeloid differentiation is mediated by protein kinase
C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and
-eta. J Biol Chem. 1993 Sep 25;268(27):20110-5. PubMed PMID: 8376369.

272: Kazanietz MG, Areces LB, Bahador A, Mischak H, Goodnight J, Mushinski JF,
Blumberg PM. Characterization of ligand and substrate specificity for the
calcium-dependent and calcium-independent protein kinase C isozymes. Mol
Pharmacol. 1993 Aug;44(2):298-307. PubMed PMID: 8355667.

273: Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller
G, Marmé D, Rapp UR. Protein kinase C alpha activates RAF-1 by direct
phosphorylation. Nature. 1993 Jul 15;364(6434):249-52. PubMed PMID: 8321321.

274: Mischak H, Goodnight J, Henderson DW, Osada S, Ohno S, Mushinski JF. Unique
expression pattern of protein kinase C-theta: high mRNA levels in normal mouse
testes and in T-lymphocytic cells and neoplasms. FEBS Lett. 1993 Jul
12;326(1-3):51-5. PubMed PMID: 8325388.

275: Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marmé
D, Schächtele C. Selective inhibition of protein kinase C isozymes by the
indolocarbazole Gö 6976. J Biol Chem. 1993 May 5;268(13):9194-7. PubMed PMID:
8486620.

276: Weissinger EM, Mischak H, Goodnight J, Davidson WF, Mushinski JF. Addition
of constitutive c-myc expression to Abelson murine leukemia virus changes the
phenotype of the cells transformed by the virus from pre-B-cell lymphomas to
plasmacytomas. Mol Cell Biol. 1993 Apr;13(4):2578-85. PubMed PMID: 8455630;
PubMed Central PMCID: PMC359590.

277: Mischak H, Goodnight JA, Kolch W, Martiny-Baron G, Schaechtle C, Kazanietz
MG, Blumberg PM, Pierce JH, Mushinski JF. Overexpression of protein kinase
C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth,
morphology, anchorage dependence, and tumorigenicity. J Biol Chem. 1993 Mar
25;268(9):6090-6. PubMed PMID: 8454583.

278: Ozawa K, Szallasi Z, Kazanietz MG, Blumberg PM, Mischak H, Mushinski JF,
Beaven MA. Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C
mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells.
Reconstitution of secretory responses with Ca2+ and purified isozymes in washed
permeabilized cells. J Biol Chem. 1993 Jan 25;268(3):1749-56. PubMed PMID:
8420951.

279: Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF, Mischak H. The cDNA
sequence, expression pattern and protein characteristics of mouse protein kinase
C-zeta. Gene. 1992 Dec 15;122(2):305-11. PubMed PMID: 1487145.

280: Dlugosz AA, Mischak H, Mushinski JF, Yuspa SH. Transcripts encoding protein
kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and
differentiating mouse keratinocytes in vitro and exhibit quantitative changes in
neoplastic cells. Mol Carcinog. 1992;5(4):286-92. PubMed PMID: 1379814.

281: Mischak H, Kolch W, Goodnight J, Davidson WF, Rapp U, Rose-John S, Mushinski
JF. Expression of protein kinase C genes in hemopoietic cells is cell-type- and B
cell-differentiation stage specific. J Immunol. 1991 Dec 1;147(11):3981-7. PubMed
PMID: 1940380.

282: Weissinger EM, Mischak H, Largaespada DA, Kaehler DA, Mitchell T, Smith-Gill
SJ, Risser R, Mushinski JF. Induction of plasmacytomas secreting antigen-specific
monoclonal antibodies with a retrovirus expressing v-abl and c-myc. Proc Natl
Acad Sci U S A. 1991 Oct 1;88(19):8735-9. PubMed PMID: 1924333; PubMed Central
PMCID: PMC52584.

283: Mischak H, Bodenteich A, Kolch W, Goodnight J, Hofer F, Mushinski JF. Mouse
protein kinase C-delta, the major isoform expressed in mouse hemopoietic cells:
sequence of the cDNA, expression patterns, and characterization of the protein.
Biochemistry. 1991 Aug 13;30(32):7925-31. PubMed PMID: 1868068.

284: Mischak H, Kolch W, Hofer F, Weissinger E, Gessl A, Davidson WF, Aiello FB,
Blaas D, Rapp UR. A raf/myc virus immortalized macrophage cell line which
supports the growth of B-cell and B-cell hybridomas. Oncogene. 1990
Sep;5(9):1377-82. PubMed PMID: 2216460.

285: Kolch W, Weissinger E, Mischak H, Troppmair J, Showalter SD, Lloyd P,
Heidecker G, Rapp UR. Probing structure and function of the raf protein kinase
domain with monoclonal antibodies. Oncogene. 1990 May;5(5):713-20. PubMed PMID:
1693184.

286: Largaespada D, Kaehler D, Weissinger E, Mischak H, Mushinski F, Risser R.
The activity of an ABL-MYC retrovirus in fibroblast cell lines and in
lymphocytes. Curr Top Microbiol Immunol. 1990;166:91-6. PubMed PMID: 2073821.

287: Weissinger EM, Largaespada D, Smith-Gill SJ, Risser R, Mushinski JF, Mischak
H. A retrovirus expressing v-abl and c-myc induces plasmacytomas in 100% of adult
pristane-primed BALB/c mice. Curr Top Microbiol Immunol. 1990;166:121-7. PubMed
PMID: 2073789.

288: Mischak H, Hofer F, Messner R, Weissinger E, Hayn M, Tomme P, Esterbauer H,
Küchler E, Claeyssens M, Kubicek CP. Monoclonal antibodies against different
domains of cellobiohydrolase I and II from Trichoderma reesei. Biochim Biophys
Acta. 1989 Jan 27;990(1):1-7. PubMed PMID: 2914146.

289: Mischak H, Neubauer C, Berger B, Kuechler E, Blaas D. Detection of the human
rhinovirus minor group receptor on renaturing Western blots. J Gen Virol. 1988
Oct;69 ( Pt 10):2653-6. PubMed PMID: 2844972.

290: Mischak H, Neubauer C, Kuechler E, Blaas D. Characteristics of the minor
group receptor of human rhinoviruses. Virology. 1988 Mar;163(1):19-25. PubMed
PMID: 2831654.

291: Kowalski H, Maurer-Fogy I, Zorn M, Mischak H, Kuechler E, Blaas D. Cleavage
site between VP1 and P2A of human rhinovirus is different in serotypes 2 and 14.
J Gen Virol. 1987 Dec;68 ( Pt 12):3197-200. PubMed PMID: 2826658.