266.

Krochmal M, Schanstra JP, Mischak H.

Urinary peptidomics in kidney disease and drug research.

Expert Opin Drug Discov. 2017 Dec 19:1-10. doi: 10.1080/17460441.2018.1418320. [Epub ahead of print] PubMed PMID: 29240457.

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265.

Magalhães P, Pejchinovski M, Markoska K, Banasik M, Klinger M, Švec-Billá D, Rychlík I, Rroji M, Restivo A, Capasso G, Bob F, Schiller A, Ortiz A, Perez-Gomez MV, Cannata P, Sanchez-Niño MD, Naumovic R, Brkovic V, Polenakovic M, Mullen W, Vlahou A, Zürbig P, Pape L, Ferrario F, Denis C, Spasovski G, Mischak H, Schanstra JP.

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

Sci Rep. 2017 Dec 5;7(1):16915. doi: 10.1038/s41598-017-17083-w. PubMed PMID: 29208969; PubMed Central PMCID: PMC5717105.

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264.

Krochmal M, Kontostathi G, Magalhães P, Makridakis M, Klein J, Husi H, Leierer J, Mayer G, Bascands JL, Denis C, Zoidakis J, Zürbig P, Delles C, Schanstra JP, Mischak H, Vlahou A.

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy.

Sci Rep. 2017 Nov 9;7(1):15160. doi:10.1038/s41598-017-15359-9. PubMed PMID: 29123184; PubMed Central PMCID: PMC5680307.

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263.

Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Charturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker.

Kidney Int Rep. 2017 Nov;2(6):1066-1075. doi: 10.1016/j.ekir.2017.06.004. PubMed PMID: 29130072; PubMed Central PMCID: PMC5669285.

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262.
Cherney D, Perkins BA, Lytvyn Y, Heerspink H, Rodríguez-Ortiz ME, Mischak H.
The effect of sodium/glucose cotransporter 2 (SGLT2) inhibition on the urinary proteome.
PLoS One. 2017 Oct 30;12(10):e0186910. doi: 10.1371/journal.pone.0186910. eCollection 2017. PMID: 29084249 Free Article

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260.
Markoska K, Pejchinovski M, Pontillo C, Zürbig P, Jacobs L, Smith A, Masin-Spasovska J, Stojceva-Taneva O, Polenakovic M, Magni F, Mischak H, Spasovski G.
Urinary peptide biomarker panel associated with an improvement in estimated glomerular filtration rate in chronic kidney disease patients.
Nephrol Dial Transplant. 2017 Sep 1. doi: 10.1093/ndt/gfx263. [Epub ahead of print] PMID: 28992073

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258.
Zhang ZY, Ravassa S, Pejchinovski M, Yang WY, Zürbig P, López B, Wei FF, Thijs L, Jacobs L, González A, Voigt JU, Verhamme P, Kuznetsova T, Díez J, Mischak H, Staessen JA.
A Urinary Fragment of Mucin-1 Subunit α Is a Novel Biomarker Associated With Renal Dysfunction in the General Population.
Kidney Int Rep. 2017 Sep;2(5):811-820. doi: 10.1016/j.ekir.2017.03.012. PMID: 28920100 Free PMC Article

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257.
Krochmal M, Cisek K, Filip S, Markoska K, Orange C, Zoidakis J, Gakiopoulou C, Spasovski G, Mischak H, Delles C, Vlahou A, Jankowski J.
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis.
Sci Rep. 2017 Aug 22;7(1):9091. doi: 10.1038/s41598-017-09393-w. PMID: 28831120 Free PMC Article

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254.
Latosinska A, Hulko M, Speidel R, Mischak H, Storr M, Krause B.
Removal of Cell-Activating Substances Using Dialyzers With Various Permeability Profiles.
Artif Organs. 2017 Jul 26. doi: 10.1111/aor.12952. [Epub ahead of print] PMID: 28744941

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253.
Pontillo C, Mischak H.
Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease.
Clin Kidney J. 2017 Apr;10(2):192-201. doi: 10.1093/ckj/sfx002. Epub 2017 Mar 29. PMID: 28694965 Free PMC Article

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251.
Wei R, Gao B, Shih F, Ranger A, Dearth A, Mischak H, Siwy J, Wisniacki N, Petri M, Burkly LC.
Alterations in urinary collagen peptides in lupus nephritis subjects correlate with renal dysfunction and renal histopathology.
Nephrol Dial Transplant. 2017 Sep 1;32(9):1468-1477. doi: 10.1093/ndt/gfw446. PMID: 28339802

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244.
Lindhardt M, Persson F, Oxlund C, Jacobsen IA, Zürbig P, Mischak H, Rossing P, Heerspink HJ.
Predicting albuminuria response to spironolactone treatment with urinary proteomics in patients with type 2 diabetes and hypertension.
Nephrol Dial Transplant. 2017 Jan 7. pii: gfw406. doi: 10.1093/ndt/gfw406. [Epub ahead of print] PMID: 28064163

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241.
Magalhães P, Mischak H, Zürbig P.
Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases.
Curr Opin Nephrol Hypertens. 2016 Nov;25(6):494-501.

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240.
Magalhães P, Mischak H, Zürbig P.
Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases.
Curr Opin Nephrol Hypertens. 2016 Nov;25(6):494-501.

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238.
Ortiz A, Husi H, Gonzalez-Lafuente L, Valiño-Rivas L, Fresno M, Sanz AB, Mullen W, Albalat A, Mezzano S, Vlahou T, Mischak H, Sanchez-Niño MD.
Mitogen-Activated Protein Kinase 14 Promotes AKI.
J Am Soc Nephrol. 2016 Sep 12. pii: ASN.2015080898. [Epub ahead of print]

 

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237.
Krochmal M, Fernandes M, Filip S, Pontillo C, Husi H, Zoidakis J, Mischak H, Vlahou A, Jankowski J.
PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease.
Database (Oxford). 2016 Sep 1;2016. pii: baw128. doi: 10.1093/database/baw128. Print 2016.

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236.
Klein J, Ramirez-Torres A, Ericsson A, Huang Y, Breuil B, Siwy J, Mischak H, Peng XR, Bascands JL, Schanstra JP.
Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice.
Kidney Int. 2016 Nov;90(5):1045-1055. doi: 10.1016/j.kint.2016.06.023.

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235.
Currie G, Flynn J, Lindhardt M, Mischak H, Rossing P, Delles C.
[OP.1D.10] THE CKD273 URINARY PROTEOMIC CLASSIFIER IS NOT A MARKER OF GENERALISED VASCULAR DISEASE IN TYPE 2 DIABETIC PATIENTS WITH NORMAL RENAL FUNCTION.
J Hypertens. 2016 Sep;34 Suppl 2:e14. doi: 10.1097/01.hjh.0000491365.78962.52.

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234.
Lindhardt M, Persson F, Zürbig P, Stalmach A, Mischak H, de Zeeuw D, Lambers Heerspink H, Klein R, Orchard T, Porta M, Fuller J, Bilous R, Chaturvedi N, Parving HH, Rossing P.
Urinary proteomics predict onset of microalbuminuria in normoalbuminuric type 2 diabetic patients, a sub-study of the DIRECT-Protect 2 study.
Nephrol Dial Transplant. 2016 Aug 8. pii: gfw292. [Epub ahead of print]

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233.
Pontillo C, Jacobs L, Staessen JA, Schanstra JP, Rossing P, Heerspink HJ, Siwy J, Mullen W, Vlahou A, Mischak H, Vanholder R, Zürbig P, Jankowski J.
A urinary proteome-based classifier for the early detection of decline in glomerular filtration.
Nephrol Dial Transplant. 2016 Jul 6. pii: gfw239. [Epub ahead of print]

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232.
Pejchinovski M, Siwy J, Metzger J, Dakna M, Mischak H, Klein J, Jankowski V, Bae KT, Chapman AB, Kistler AD.
Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression.
Nephrol Dial Transplant. 2016 Jul 5. pii: gfw243. [Epub ahead of print]

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230.
Pena MJ, Mischak H, Heerspink HJ.
Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease.
Diabetologia. 2016 Sep;59(9):1819-31. doi: 10.1007/s00125-016-4001-9. Epub 2016 Jun 25. Review.

 

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228.
Metzger J, Mullen W, Husi H, Stalmach A, Herget-Rosenthal S, Groesdonk HV, Mischak H, Klingele M.
Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study.
Crit Care. 2016 May 26;20(1):157. doi: 10.1186/s13054-016-1344-z.

 

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227.
Farmakis D, Koeck T, Mullen W, Parissis J, Gogas BD, Nikolaou M, Lekakis J, Mischak H, Filippatos G.
Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates.
Eur J Heart Fail. 2016 Jul;18(7):822-9. doi: 10.1002/ejhf.544. Epub 2016 May 25.

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216.
Cisek K, Krochmal M, Klein J, Mischak H.
The application of multi-omics and systems biology to identify therapeutic targets in chronic kidney disease.
Nephrol Dial Transplant. 2015 Oct 20. pii: gfv364. [Epub ahead of print] Review.

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209.
Øvrehus MA, Zürbig P, Vikse BE, Hallan SI.
Urinary proteomics in chronic kidney disease: diagnosis and risk of progression beyond albuminuria.
Clin Proteom (2015) 12:21. doi: 10.1186/s12014-015-9092-7

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208.
Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés À, Vanholder R, Vlahou A, Klein J.
New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis.
Nephrol Dial Transplant. 2015 Jul 9. pii: gfv254. [Epub ahead of print]

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203.
Mischak H
Pro: Urine proteomics as a liquid kidney biopsy: no more kidney punctures!
Nephrol. Dial. Transplant. (2015) 30 (4): 532-537 doi:10.1093/ndt/gfv046

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194.
Silva S, Bronze MR, Figueira ME, Siwy J, Mischak H, Combet E, Mullen W.
Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study.
Am J Clin Nutr. 2015 Jan;101(1):44-54. doi: 10.3945/ajcn.114.094219. Epub 2014 Nov 19.

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185.
Gu YM, Thijs L, Liu YP, Zhang Z, Jacobs L, Koeck T, Zürbig P, Lichtinghagen R, Brand K, Kuznetsova T, Olivi L, Verhamme P, Delles C, Mischak H, Staessen JA.
The urinary proteome as correlate and predictor of renal function in a population study.
Nephrol Dial Transplant. 2014 Jun 30. pii: gfu234. [Epub ahead of print]

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184.
Filip S, Pontillo C, Peter Schanstra J, Vlahou A, Mischak H, Klein J.
Urinary proteomics and molecular determinants of chronic kidney disease: possible link to proteases.
Expert Rev Proteomics. 2014 Jun 24:1-14. [Epub ahead of print]

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182.
Nkuipou-Kenfack E, Duranton F, Gayrard N, Argilés A, Lundin U, Weinberger KM, Dakna M, Delles C, Mullen W, Husi H, Klein J, Koeck T, Zürbig P, Mischak H.
Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease.
PLoS One. 2014 May 9;9(5):e96955. doi: 10.1371/journal.pone.0096955. eCollection 2014.

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181.
Mullen W, Saigusa D, Abe T, Adamski J, Mischak H.
Proteomics and Metabolomics as Tools to Unravel Novel Culprits and Mechanisms of Uremic Toxicity: Instrument or Hype?
Semin Nephrol. 2014 Mar;34(2):180-190. doi: 10.1016/j.semnephrol.2014.02.009. Epub 2014 Feb 18. Review.

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180.
Schanstra JP, Mischak H.
Proteomic urinary biomarker approach in renal disease: from discovery to implementation.
Pediatr Nephrol. 2014 Mar 15. [Epub ahead of print]

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179.
Siwy J, Schanstra JP, Argiles A, Bakker SJ, Beige J, Boucek P, Brand K, Delles C, Duranton F, Fernandez-Fernandez B, Jankowski ML, Al Khatib M, Kunt T, Lajer M, Lichtinghagen R, Lindhardt M, Maahs DM, Mischak H, Mullen W, Navis G, Noutsou M, Ortiz A, Persson F, Petrie JR, Roob JM, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Snell-Bergeon J, Spasovski G, Stojceva-Taneva O, Trillini M, von der Leyen H, Winklhofer-Roob BM, Zürbig P, Jankowski J.
Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy.
Nephrol Dial Transplant. 2014 Mar 2. [Epub ahead of print]

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175.
Klein J, Buffin-Meyer B, Mullen W, Carty DM, Delles C, Vlahou A, Mischak H, Decramer S, Bascands JL, Schanstra JP.
Clinical proteomics in obstetrics and neonatology.
Expert Rev Proteomics. 2014 Jan 3. [Epub ahead of print]

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174.
Frantzi M, Metzger J, Banks RE, Husi H, Klein J, Dakna M, Mullen W, Cartledge JJ, Schanstra JP, Brand K, Kuczyk MA, Mischak H, Vlahou A, Theodorescu D, Merseburger AS.
Discovery and Validation of Urinary Biomarkers for Detection of Renal Cell Carcinoma.
J Proteomics. 2013 Dec 24. pii: S1874-3919(13)00645-3. doi: 10.1016/j.jprot.2013.12.010. [Epub ahead of print]

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172.
Duranton F, Lundin U, Gayrard N, Mischak H, Aparicio M, Mourad G, Daurès JP, Weinberger KM, Argilés A.
Plasma and Urinary Amino Acid Metabolomic Profiling in Patients with Different Levels of Kidney Function.
Clin J Am Soc Nephrol. 2013 Nov 14. [Epub ahead of print]

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170.
Husi H, Sanchez-Niño MD, Delles C, Mullen W, Vlahou A, Ortiz A, Mischak H.
A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI.
BMC Syst Biol. 2013 Oct 30;7(1):110. [Epub ahead of print]

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169.
Dissard R, Klein J, Caubet C, Breuil B, Siwy J, Hoffman J, Sicard L, Ducassé L, Rascalou S, Payre B, Buléon M, Mullen W, Mischak H, Tack I, Bascands JL, Buffin-Meyer B, Schanstra JP.
Long Term Metabolic Syndrome Induced by a High Fat High Fructose Diet Leads to Minimal Renal Injury in C57BL/6 Mice.
PLoS One. 2013 Oct 3;8(10):e76703.

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166.
Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B, Stalmach A, Mullen W, Mischak H, Bandin F, Monsarrat B, Bascands JL, Decramer S, Schanstra JP.
Fetal Urinary Peptides to Predict Postnatal Outcome of Renal Disease in Fetuses with Posterior Urethral Valves (PUV).
Sci Transl Med. 2013 Aug 14;5(198):198ra106. doi: 10.1126/scitranslmed.3005807.

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165.
Albalat A, Stalmach A, Bitsika V, Siwy J, Schanstra JP, Petropoulos AD, Vlahou A, Jankowski J, Persson F, Rossing P, Jaskolla TW, Mischak H, Husi H.
Improving peptide relative quantification in MALDI-TOF MS for biomarker assessment.
Proteomics. 2013 Aug 14. doi: 10.1002/pmic.201300100. [Epub ahead of print]

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159.
Argilés A, Siwy J, Duranton F, Gayrard N, Dakna M, Lundin U, Osaba L, Delles C, Mourad G, Weinberger KM, Mischak H.
CKD273, a New Proteomics Classifier Assessing CKD and Its Prognosis.
PLoS One. 2013 May 14;8(5):e62837. doi: 10.1371/journal.pone.0062837. Print 2013.

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155.
Kistler AD, Serra AL, Siwy J, Poster D, Krauer F, Torres VE, Mrug M, Grantham JJ, Bae KT, Bost JE, Mullen W, Wüthrich RP, Mischak H, Chapman AB.
Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study.
PLoS One. 2013;8(1):e53016. doi: 10.1371/journal.pone.0053016. Epub 2013 Jan 10.
         
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151.
Roscioni SS, de Zeeuw D, Hellemons ME, Mischak H, Zürbig P, Bakker SJ, Gansevoort RT, Reinhard H, Persson F, Lajer M, Rossing P, Heerspink HJ.
A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus.
Diabetologia. 2013 Feb;56(2):259-67. doi: 10.1007/s00125-012-2755-2. Epub 2012 Oct 20.

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149.
Herget-Rosenthal S, Metzger J, Albalat A, Bitsika V, Mischak H.
Proteomic biomarkers for the early detection of acute kidney injury.
Prilozi. 2012 Jul;33(1):27-48.
         
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148.
Duranton F, Cohen G, De Smet R, Rodriguez M, Jankowski J, Vanholder R, Argiles A; European Uremic Toxin Work Group.
Normal and pathologic concentrations of uremic toxins.
J Am Soc Nephrol. 2012 Jul;23(7):1258-70. Epub 2012 May 24.
         
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145.
Zürbig P, Jerums G, Hovind P, MacIsaac R, Mischak H, Nielsen SE, Panagiotopoulos S, Persson F, Rossing P.
 Urinary Proteomics for Early Diagnosis in Diabetic Nephropathy.
Diabetes. 2012 Dec;61(12):3304-13. doi: 10.2337/db12-0348. Epub 2012 Aug 7.
         
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134.
Bandin F, Siwy J, Breuil B, Mischak H, Bascands JL, Decramer S, Schanstra JP
Urinary Proteome Analysis at 5-Year Followup of Patients With Nonoperated Ureteropelvic Junction Obstruction Suggests Ongoing Kidney Remodeling.
Pediatrics. 2012 Feb;129(2):e356-63. Epub 2012 Jan 23.

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131.
Drube J, Schiffer E, Lau E, Petersen C, Kirschstein M, Kemper M, Lichtinghagen R, Ure B, Mischak H, Pape L, Ehrich JH
Urinary Proteome Analysis to Exclude Severe Vesicoureteral Reflux
 Pediatrics. 2012 Feb;129(2):e356-63. Epub 2012 Jan 23.  

         
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129.
Mullen W, Delles C, Mischak H; members of EuroKUP COST action.
Urinary proteomics in the assessment of chronic kidney disease.
Curr Opin Nephrol Hypertens. 2011 Nov;20(6):654-61.
         
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 124.
Mischak H, Thongboonkerd V, Schanstra JP, Vlahou A
Renal and urinary proteomics.
Proteomics Clin Appl. 2011 Jun;5(5-6):211-3. doi: 10.1002/prca.201190031.
         
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123.
Zürbig P, Dihazi H, Metzger J, Thongboonkerd V, Vlahou A
Urine proteomics in kidney and urogenital diseases: Moving towards clinical applications.
Proteomics Clin Appl. 2011 Jun;5(5-6):256-68. doi: 10.1002/prca.201000133. Epub 2011 May 18.         

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122.
Schiffer E, Liabeuf S, Lacroix C, Temmar M, Renard C, Monsarrat B, Choukroun G, Lemke HD, Vanholder R, Mischak H, Massy ZA; on behalf of the European Uremic Toxin Work Group (EUTox).
Markers of vascular disease in plasma from patients with chronic kidney disease identified by proteomic analysis.
J Hypertens. 2011 Apr;29(4):783-790
         
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120.
Ehrich JH, Schiffer E, Drube J.
Urinary proteomics : The diagnostic key for urinary tract abnormalities and kidney diseases in children?
Urologe A. 2011 Feb;50(2):170-179
         
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115.
Foucher C, Schiffer E, Mischak H, Ansquer JC, Wilbraham D
Effect of fenofibrate treatment on the low molecular weight urinary proteome of healthy volunteers
Proteomics Clinical Applications 2011
         
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111.
Andersen S, Mischak H, Zuerbig P, Parving HH, Rossing P
Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria
BMC Nephrology 2010, 11:29
         
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110.
Alkhalaf A, Zuerbig P, Bakker SJL, Bilo HJG, Cerna M, Fischer C, Fuchs S, Janssen B, Medek K, Mischak H, Roob JM, Rossing K, Rossing P, Rychlík I, Sourij H, Tiran B, Winklhofer-Roob BM, Navis GJ
Multicentric Validation of Proteomic Biomarkers in Urine Specific for Diabetic Nephropathy
PLoS ONE 2010 Oct; 5(10): e13421
         
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109.
Maahs DM, Siwy J, Argilés À, Cerna M, Delles C, Dominiczak AF, Gayrard N, Iphöfer A, Jänsch L, Jerums G, Medek K, Mischak H, Navis G, Roob JM, Rossing K, Rossing P, Rychlík I, Schiffer E, Schmieder RE, Wascher TC, Winklhofer-Roob BM, Zimmerli LU, Zürbig P, Snell-Bergeon JK
Urinary Collagen Fragments are Significantly Altered in Diabetes: a Link to Pathophysiology
PLoS ONE 2010 Sep; 5(9). pii: e13051
         
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104.
Mischak H, Rossing P. 
Proteomic biomarkers in diabetic nephropathy - reality or future promise?
The Journal of biological chemistry 2010 March
         
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101.
Good DM, Zürbig P, Argilés A, Bauer HW, Behrens G, Coon JJ, Dakna M, Decramer S, Delles C, Dominiczak AF, Ehrich JHH, Eitner F, Fliser D, Frommberger M, Ganser A, Girolami MA, Golovko I, Gwinner W, Haubitz M, Herget-Rosenthal S, Jankowski J, Jahn H, Jerums G, Julian BA, Kellmann M, Kliem V, Kolch W, Krolewski AS, Luppi M, Massy Z, Melter M, Neusüss C, Novak J, Peter K, Rossing K, Rupprecht H , Schanstra JP, Schiffer E, Stolzenburg JU, Tarnow L, Theodorescu D, Thongboonkerd V, Vanholder R, Weissinger EM, Mischak H, Schmitt-Kopplin P
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease.
Mol Cell Proteomics. 2010 Nov;9(11):2424-37. Epub 2010 Jul 8.
         
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99.
Caubet C, Lacroix C, Decramer S, Drube J, Ehrich JHH, Mischak H, Bascands JL, Schanstra JP
Advances in urinary proteome analysis and biomarker discovery in pediatric renal disease.
Pediatr Nephrol. 2010 Jan;25(1):27-35
         
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98.
Drube J, Zürbig P, Schiffer E, Lau E, Ure B, Glüer S, Kirschstein M, Pape L, Decramer S, Bascands JL, Schanstra JP, Mischak H, Ehrich JH.
Urinary proteome analysis identifies infants but not older children requiring pyeloplasty.
Pediatr Nephrol. 2010 Sep;25(9):1673-8. Epub 2010 Feb 24.
         
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96.
Zürbig P, Mischak H, Conrads S
Urinary proteome analysis for early diagnosis of diabetes and its complications
Diabetes, Stoffwechsel und Herz, Band 18, 6/2009
         
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91.
Jankowski V, Giet M, Mischak H, Morgan M, Zidekm W, Jankowski J
Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system (review)
Br J Pharmacol. 2009 Aug;157(7):1142-53. Epub 2009 Jun 25.
         
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90.
Caubet C, Lacroix C, Decramer S, Drube J, Ehrich JHH, Mischak H, Bascands JL, Schanstra JP
Advances in urinary proteome analysis and biomarker discovery in pediatric renal disease.
Pediatr Nephrol. 2010 Jan;25(1):27-35. Epub 2009 Jul 15.
         
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89.
Haubitz M, Good DM, Woywodt A, Haller H, Rupprecht H, Theodorescu D, Dakna M, Coon J, Mischak H
Identification and Validation of Urinary Biomarkers for Differential Diagnosis and Evaluation of Therapeutic Intervention in ANCA associated Vasculitis
Mol Cell Proteomics. 2009 Oct;8(10):2296-307. Epub 2009 Jun 28.
         
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87.
Kistler A, Mischak H, Poster D, Dakna M, Wuthrich R, Serra A
Identification of a unique urinary biomarker profile in autosomal dominant polycystic kidney disease
Kidney Int. 2009 Jul;76(1):89-96
         
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84.
Drube J, Schiffer E, Mischak H, Kemper M, Neuhaus T, Pape L, Lichtinghagen R, Ehrich JHH
Urinary proteome pattern in children with renal Fanconi syndrome
Nephrol Dial Transplant. 2009 Jul;24(7):2161-9. Epub 2009 Feb 18
         
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82.
Mischak H, Massy ZA, Jankowski J
Proteomics and uremia and renal disease
Seminars in Dialysis 2009
         
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81.
Zürbig P, Decramer S, Dakna M, Jantos J, Good DM, Coon JJ, Bandin F, Mischak H, Bascands JL, Schanstra JP.
The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease.
Proteomics. 2009 Apr;9(8):2108-17
         
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78.
Snell-Bergeon JK, Maahs DM, Ogden LG, Kinney GL, Hokanson JE, Schiffer E, Mischak H, Rewers M
Evaluation of urinary biomarkers for coronary artery disease, diabetes, and diabetic kidney disease
Diabetes, Technology and Therapeutics 2009, 11(1): 1-9
         
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76.
Jantos-Siwy J, Schiffer E, Brand K, Schumann G, Rossing K, Delles C, Mischak H, Metzger J
Quantitative urinary proteome analysis for biomarker evaluation in chronic kidney disease
Journal of Proteome Research 2009, 8(1): 268-281
         
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74.
Haubitz M, Mischak H, Julian BA, Novak J
Urinary Protein Patterns as a Diagnostic Tool for Patients with Immunoglobulin A Nephropathy
Rapid Commun Mass Spectrom. 2010 Jul 30;24(14):1971-8.
         
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68.
Schiffer E, Mischak H, Vanholder RC
Exploring the uremic toxins using proteomic technologies
Contrib Nephrol. 2008, 160: 159-171
         
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67.
Decramer S, Zurbig P, Wittke S, Mischak H, Bascands JL, Schanstra JP
Identification of urinary biomarkers by proteomics in newborns: use in obstructive nephropathy
Contrib Nephrol. 2008, 160: 127-141
         
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66.
Zurbig P, Mischak H
Capillary electrophoresis coupled to mass spectrometry for biomarker discovery and diagnosis of kidney diseases
Contrib Nephrol. 2008, 160: 107-126
         
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65.
Rossing K, Mischak H, Rossing P, Schanstra JP, Wiseman A, Maahs DM
The urinary proteome in diabetes and diabetes-associated complications: new ways to assess disease progression and evaluate therapy
PROTEOMICS - Clinical Applications 2008, 2(7-8): 997-1007
         
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64.
Raedler T, Wittke S, Jahn H, Kössler A, Mischak H, Wiedemann K
Capillary electrophoresis mass spectrometry as a potential tool to detect lithium-induced nephropathy: Preliminary results
Prog Neuropsychopharmacol Biol Psychiatry 2008, 32(3): 673-678
         
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63.
Rossing K, Mischak H, Dakna M, Zürbig P, Novak J, Julian BA, Good DM, Coon JJ, Tarnow L, Rossing P
Proteomic Discovery and Evaluation of Urinary Biomarkers for Diabetes and Chronic Renal Disease
J Am Soc Nephrol. 2008, 19(7): 1283-1290
         
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56.
Julian BA, Wittke S, Novak J, Good D, Coon JJ, Kellmann M, Zurbig P, Schiffer E, Haubitz M, Moldoveanu Z, Calcatera S, Wyatt R, Sykora J, Sladkova E, Hes O, Mischak H, Mc Guire B
Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases
Electrophoresis 2007, 28(23): 4469-4483
         
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54.
Vanholder R, Meert N, Schepers E, Glorieux G, Argiles A, Brunet P, Cohen G, Drueke T, Mischak H, Spasovski G, Massy Z, Jankowski J; for the European Uremic Toxin Work Group (EUTox)
Review on uraemic solutes II Variability in reported concentrations: causes and consequences
Nephrol Dial Transplant. 2007, 22(11): 3115-3121
         
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51.
Julian BA, Wittke S, Haubitz M, Zurbig P, Schiffer E, McGuire BM, Wyatt RJ, Novak J
Urinary biomarkers of IgA nephropathy and other IgA-associated renal diseases
World Journal of Urology 2007, 35(5): 467-476
         
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50.
Decramer S, Bascands JL, Schanstra JP
Non-invasive markers of ureteropelvic junction obstruction
World Journal of Urology 2007, 25(5): 457-465
         
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44.
Fliser D, Novak J, Thongboonkerd V, Argiles A, Jankowski V, Girolami MA, Jankowski J, Mischak H
Advances in urinary proteome analysis and biomarker discovery
J Am Soc Nephrol. 2007, 18(4): 1057-1071
         
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43.
Mischak H, Pantke U, Fliser D
Proteomanalyse zur Erkennung, Früherkennung und Therapieevaluierung der diabetischen Nephropathie
journal of preventive medicine 2007, 3(1): 28-35
         
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33.
Decramer S, Wittke S, Mischak H, Zurbig P, Walden M, Bouissou F, Bascands JL, Schanstra JP
Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis
Nat Med. 2006, 12(4): 398-400
         
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30.
Weissinger EM, Nguyen-Khoa T, Saltiel C, Buisson C, Walden M, Kaiser T, Mischak H, Drüeke TB, Lacour B, Massy ZA
Effects of oral vitamin C supplementation on oxidative stress and inflammation status in hemodialysis patients – Classical and proteomic assessment
Proteomics 2006, 6(3): 993-1000
         
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28.
Walden M, Wittke S, Mischak H, Vanholder RC
Proteomics of human dialysate and ultrafiltrate fluids yielded by renal replacement therapy
Thongboonkerd V (Ed.) 2006, Proteomics of Human Body Fluids: Principles, Methods, and Applications
         
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25.
Chalmers MJ, Mackay CL, Hendrickson CL, Wittke S, Walden M, Mischak H, Fliser D, Just I, Marshall AG
Combined top-down and bottom-up mass spectrometric approach to characterization of biomarkers for renal disease
Anal Chem. 2005, 77(22): 7163-7171
         
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23.
Wittke S, Haubitz M, Walden M, Rohde F, Schwarz A, Mengel M, Mischak H, Haller H, Gwinner W
Detection of acute tubulointerstitial rejection by proteomic analysis of urinary samples in renal transplant recipients
Am J Transplant. 2005, 5(10): 2479-2488
         
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22.
Meier M, Kaiser T, Herrmann A, Knueppel S, Hillmann M, Koester P, Danne T, Haller H, Fliser D, Mischak H
Identification of urinary protein pattern in type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysis
J Diabetes Complications. 2005, 19(4): 223-232
         
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21.
Rossing K, Mischak H, Parving HH, Christensen PK, Walden M, Hillmann M, Kaiser T
Impact of diabetic nephropathy and angiotensin II receptor blockade on urinary polypeptide patterns
Kidney Int. 2005, 68(1): 193-205
         
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18.
Haubitz M, Wittke S, Weissinger EM, Walden M, Rupprecht HD, Floege J, Haller H, Mischak H
Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy
Kidney Int. 2005, 67(6): 2313-2320
         
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15.
Hillman M, Mischak H
CE-MS as a Tool for Renal Disease Analysis and Biomarker Discovery Pace Setter
The worldwide newsletter for capillary electrophoresis (Beckman Coulter) 2005, 9(2): 1-5
         
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13.
Weissinger EM, Kaiser T, Meert N, De Smet R, Walden M, Mischak H, Vanholder RC
Proteomics: a novel tool to unravel the patho-physiology of uraemia
Nephrol Dial Transplant. 2004, 19(12): 3068-3077
         
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12.
Mischak H, Kaiser T, Walden M, Hillmann M, Wittke S, Herrmann A, Knueppel S, Haller H, Fliser D
Proteomic analysis for the assessment of diabetic renal damage in humans
Clin Sci (Lond). 2004, 107(5): 485-495
         
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8.
Weissinger EM, Wittke S, Kaiser T, Haller H, Bartel S, Krebs R, Golovko I, Rupprecht HD, Haubitz M, Hecker H, Mischak H, Fliser D
Proteomic patterns established with capillary electrophoresis and mass spectrometry for diagnostic purposes
Kidney Int. 2004, 65(6): 2426-2434
         
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7.
Haubitz M, Fliser D, Haller H
Proteomanalyse – eine neue Perspektive für die klinische Diagnostik
Deutsches Ärzteblatt 2004, 101(21): A-1514 / B-1255 / C-1207
         
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3.
Weissinger EM, Mischak H
Proteom analysis applied towards early diagnosis of renal diseases and transplant-monitoring
Transplantationsmedizin 2004, 16: 2-9
         
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2.
Kaiser T, Hermann A, Kielstein JT, Wittke S, Bartel S, Krebs R, Hausadel F, Hillmann M, Golovko I, Koester P, Haller H, Weissinger EM, Fliser D, Mischak H
Capillary electrophoresis coupled to mass spectrometry to establish polypeptide patterns in dialysis fluids
J Chromatogr A. 2003, 1013(1-2): 157-171
         
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