Renal Transplant Rejection

It is important that any post-transplantation complications, such as rejection, be identified as early as possible so that appropriate therapy can be initiated. Currently definite identification of such complications involves the analysis of biopsies, which is not suitable for repetitive monitoring. Our CE-MS technique has enabled the identification of a specific peptide pattern that can distinguish rejection in kidney transplant patients. As a consequence of our findings renal biopsies can be replaced by urine analysis.