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R&D Projects

Mosaiques diagnostics is member/participant of a multitude of respectable consortia and research projects and during our time in the field of clinical proteomics we achieved a valued position in several renowned scientific networks.


EuroKup - European Kidney and Urine ProteomicsKidney diseases constitute a major health threat in all societies. Proteomics is the large-scale analysis of the proteins of biological samples. Application of proteomics methodologies in the investigation of renal diseases will catalyze the development of optimal diagnostic and prognostic tests. Despite preliminary successful efforts, the interactions between the multidisciplinary teams of scientists working on kidney diseases and proteomics are still limited in Europe. EUROKUP will foster the generation of a strong and growing multi disciplinary network of scientists from at least 20 European countries, focusing on renal and urine proteomics. The objectives of the Action focus on the identification of reference clinical centers for major kidney diseases and establishment of uniform clinical databases, standardization and optimization of procedures, integration of data to systems biology approaches and dissemination of information for application to diagnostic/prognostic procedures. Multiple scientific, technological and societal benefits to the European Union are expected, including but not limited to setting the urgently needed standards for clinical proteomics and translational research and improving the clinical situation in chronic kidney diseases.

 

SysKid - A Collaborative research Project to Fight Chronic Kidney Disease
SysKid (
Systems Biology towards Novel Chronic Kidney Disease Diagnosis and Treatment) a large-scale integrating European research project, aims at understanding chronic kidney disease in the context of diabetes and hypertension.


European Uremic Toxin (EUTox) Work Group of the ESAO
The European Society of Artificial Organs (ESAO) decided to install work groups in several areas of progress in the field of artificial organs, such as artificial liver, heart support, apheresis and adsorption, tissue engineering, education and uremic toxins.


Geninca
Mechanisms and markers of GENomic INstability in gastrointestinal pre-cancerous lesions and CAncer as targets for novel therapeutic and prevention strategies and for improved tumor diagnosis and monitoring.


INCA Project
The role of chronic infections in the development of cancer:
INCA Project (data exchange)


InGenious HyperCare
The InGenious HyperCare Network of Excellence’s goal is that of integrating complementary but still fragmented experience in the mechanisms of blood pressure control and hypertension development, in phenotyping initiation and progression of organ damage and in exploring genetics, genomics and proteomics of proneness to hypertension and hypertension-related cardiovascular disease.


Predictions
Approximately 30% of all patients with type 2 diabetes will develop diabetic nephropathy (DN). Still there are no effective methods to determine the individual risk of developing DN.


PREDIVA

Represents a collaborative study of 9 academic and 4 industrial partners from 7 European countries. The PREDIVA consortium is dedicated to use a multidisciplinary approach, in order to extend current knowledge and develop tests aiming at the genotypic and phenotypic discrimination of subgroups of diabetics prone to develop either islet pathology or vascular complications. Translational research and development will ultimately lead to new diagnostic tools for the prediction and prognosis of type 2 diabetic complications.


STEMDIAGNOSTICS
The development of new diagnostic tests, new tools and non-invasive methods for the prevention, early diagnosis and monitoring for haematopoietic stem cell transplantation (HSCT).


UROSYSTEOMICS
Integration of Proteomics, Genomics, Transcriptomics and Metabonomics to identify and characterize early prognostic, diagnostic and therapeutic biomarkers for widespread urologic disorders.